Investigation of solid products for lycopene(2)Formulation and Dissolution of hydrophobic drugs

Chia Nan University of Pharmacy & Science Institutional Repository > 藥理學院 > 藥學系(所) > 校內計畫 > Item 310902800/1094

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標題:	Investigation of solid products for lycopene(2)Formulation and Dissolution of hydrophobic drugs 含茄紅素之固體製劑研發(2)脂溶性藥品之處方與溶離
作者:	許立人
貢獻者:	藥學系
關鍵字:	Soft capsule 軟膠囊
日期:	2003
上傳時間:	2008-06-26 10:40:07 (UTC+8)
出版者:	台南縣：嘉南藥理科技大學藥學系
摘要:	Soft capsules as a pharmaceutical dosage form have the advantages of being: high bioavailability for nonpolar drug in oil solution, stable toward oxidation and hydrolysis, and content uniformity. However, it has also some limitations such as: the raw material is animal origin, it breaks up in the stomach fast. The purpose of this study is to optimize the technology to make the soft capsule by a semi-automatic soft capsule machine. Then, add the function of controlled release to this traditional dosage form of soft capsule. Finally, do a preliminary screening study on the replacement or modification of the raw material. 軟膠囊具有，對水難溶解性藥品高生體可用率之優點，同時內容均勻且安定，空氣及溼氣對膠囊之通透性皆低。但是它也有動物來源之缺點，對素食者不適用。而且狂牛病之傳染，使得人們更有疑慮。本計劃繼續研究半自動軟膠囊機製造軟膠囊之技術，也尋找開發軟膠囊之新原料。
關聯:	計畫編號：CNPH9212
顯示於類別:	[藥學系(所)] 校內計畫

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