茉莉精油放鬆效果及其作用機轉的研究

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標題:	茉莉精油放鬆效果及其作用機轉的研究 The Study on Mechanism of Relaxation Effects of Jasmine Essential Oil
作者:	王麗惠
貢獻者:	郭俊成嘉南藥理科技大學：化妝品科技研究所
關鍵字:	放鬆茉莉精油芳香療法生理訊號 relaxation jasmine essential oil aromatherapy biosignal
日期:	2009
上傳時間:	2010-05-31 13:59:21 (UTC+8)
摘要:	本研究系為了解茉莉精油在吸嗅之後對中樞神經之抑制效果。採用戊四氮致痙動物模式，結果顯示預吸入茉莉精油能夠顯著地延遲第一級、第五級痙攣誘發的時間（P<.05，P<.01）。人體實驗則研究在腦電波-ㄙi活動、血容積搏動、心率變異（HRV：LF、HF、nLF、nHF、LF/HF、SDNN）、肌電位、皮膚電導度、呼吸率、末稍溫度、痛閾值的變化情形。在吸嗅茉莉精油芳香分子後，能夠顯著降低LF/HF值，調降呼吸率與皮膚電導度，並同時觀察到痛閾值及皮膚末稍溫度有提升的趨勢（P<.05）。ㄙi活動、肌電位、低頻?#63841;強度、高頻?#63841;強度與NN間期之標準差結果則在吸嗅茉莉精油後未達顯著變化。平均心搏與血壓在芳香療法後無顯著改變。23%的受測者喜歡茉莉香氣，13%表示討厭茉莉精油的味道，64%表示對茉莉香氣無特別的偏好與厭惡。茉莉香氣的偏好與性別組成以男女比例方式分別為43:57（喜歡茉莉香氣）、1:1（討厭茉莉香氣）、1:1（無特殊偏好）。根據受測者間的STAI分數與原始心搏數關聯性比較，顯試受測者在受測者可能處於非壓力的情緒下。結論：所有的受測者在吸嗅完I茉莉香氣後其心率與血壓維持穩定，可知個體系處於非壓力的狀態。而根據放鬆相關生理訊號的改變結果發現，吸嗅茉莉精油，或可利用抑制中樞神經的活動使人們感到放鬆，而此抑制表現不受性別、年齡、氣味偏好之影響。吸嗅茉莉精油具有與憂鬱表現相關的中樞神經抑制效果。茉莉精油的這些特質使其成為添加於化粧品的潛力成份。未來或陳鉞讕悜[莉精油的吸嗅為一改善壓力型美容問題的新方式。而此研究模式，亦提供未來研究人員另一快速、經濟篩檢精油放鬆特質的平台。 This study was performed to evaluate the inhibitory effects of central nervous system after inhalation of the essential oil from Jasmine. Animal model of Pentylenetetrazole induced convulsion has been adapted and the result shows pre-inhalation of jasmine essential oil could significantly decreased the convulsion level of the mice and delayed the appearance of the convulsion stage 1 & stage 5. （P<.05 P<.01） Human model have been studied by using alpha activity in the electroencephalogram（EEG）, blood vessel pulsation（BVP）, heart rate variability （HRV：LF、HF、nLF、nHF、LF/HF、SDNN）, electromyography（EMG）,skin conductance（SC）, respiratory rates, peripheral temperature and changes in pain threshold. After inhalation of jasmine fragrance could significantly decrease the LF/HF value, lower down the respiratory rates and skin conductance value, the increased of the pain threshold and skin temperature have been observed.（P<.05）The ?activity, EMG, LF power, HF power, SDNN show no significant change after inhalation of the jasmine odor. The average heart beat and blood pressure show no significantly change after aromatherapy. 23% of the objects like the odor of jasmine essential oil, 13% has a dislike of the smell of jasmine odor, 64% objects show no special preference of the jasmine odor. the odor preference consist of the sex III distinction on male & female of 43:57（like the odor of jasmine）, 1:1（unlike the odor of jasmine）and 1:1(no special preference). As a brief conclusion, according to the correlation between scores of STAI and original heart beats between objects shows total objects are under the same kind of non-stress level by distinguished from the stable heart rate and blood pressure after inhalation of the jasmine odor. According to the relaxing-like biological signals change, inhale the jasmine odor might make people feel relax by inhibiting the CNS activity and the inhibitory express won’t be affected by the age, sexual or the preference of the odor. Inhalation of the fragrance oil from jasmine shows inhibitory activity of the CNS related to decompression kind expression. These characteristics of jasmine essential oil make it a potential cosmetic ingredient. It give us an idea that inhalation of jasmine essential oil may help improving stress-induced skin problems in a new way. We suggest this evaluation method as a fast and cost less way for researcher to study the characteristics of essential oil.
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