日本腦炎是台灣地區重要的病毒性腦炎之一。本研究以學生為對象，採用溶斑減少中和抗體試驗法進行日本腦炎中和抗體檢測，比較對疫苗中山株抗體呈陽性或陰性個體對疫苗北京株及台灣野外株病毒的中和抗體陽性率，以及北京株抗體呈陽性或陰性個體對台灣野外株病毒的中和抗體陽性率。結果顯示疫苗北京株的中和抗體陽性率較疫苗中山株的中和抗體陽性率更能確實反應個體對野生病毒的中和能力。 Japanese encephalitis (JE) is one of
the most important encephalitis in
Taiwan. This project was to compare
seropositive rates of neutralizing
antibodies against two JE vaccine strains
(Nakayama and Beijing) and Taiwan
local JEV strains among college students
by plaque reduction neutralization tests.
The results indicated that seropositivity
against vaccine Beijing strain was the
better index than seropositivity against
vaccine Nakayama strain to reflect the
capability of individuals to neutralize
wild Taiwan JEV isolates.
