DSpace community: 嬰幼兒保育系

Early neonatal hypoglycemia in term and late preterm small for gestational age newborns

Wed, 25 Dec 2024 03:05:17 GMT

title: Early neonatal hypoglycemia in term and late preterm small for gestational age newborns abstract: Background: Neonatal hypoglycemia is a common metabolic occurrence among small for gestational age (SGA) neonates. This study aims to determine the incidence of early neonatal hypoglycemia and confirms the potential risk factors among term and late preterm SGA neonates in a well-baby newborn nursery of a tertiary medical center in Southern Taiwan.Methods: We performed a retrospective medical record review of term and late preterm SGA (birth weight <10 percentile) neonates, born between January 1, 2012 and December 31, 2020, in the well-baby newborn nursery, of a tertiary medical center in Southern Taiwan. Blood glucose monitoring was routinely performed at 0.5, 1, 2, and 4 h of life. Antenatal and postnatal risk factors were recorded. Mean blood glucose level, age of occurrence, symptomatic hypoglycemia, and need for intravenous glucose treatment of early hypoglycemia in SGA neonates were documented.Results: 690 SGA neonates in the nursery met the criteria and were retrospectively enrolled in the study, 358 of whom (51.80%) were male and 332 (48.10%) female. Of 690 enrolled SGA neonates, 134(19.42%) SGA neonates developed hypoglycemia during a well-baby nursery stay. Among these neonates, 97% of early hypoglycemic episodes occur during the first 2 h of life. The lowest blood glucose level was 46.78 +/- 11.13 mg/dL, recorded in the first hour of life. Among the hypoglycemic 134 neonates, 26 (19.40%) neonates had to be transferred from the nursery to the neonatal ward and they required intravenous glucose treatment to achieve euglycemia. 14 (10.40%) neonates had symptomatic hypoglycemia. A multivariate logistic regression analysis revealed that cesarean delivery, small head circumference, small chest circumference, and low 1-min Apgar score were significant risk factors for early hypoglycemia in these neonates.Conclusion: Periodic routine blood glucose level monitoring within the first 4 h of life in term and late preterm SGA neonates is required, especially those with cesarean delivery and low Apgar score.Copyright (c) 2023, Taiwan Pediatric Association. Published by Elsevier Taiwan LLC. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

探索與實作的融合〜將STEAM 精神融入兒童教學活動

Tue, 08 Oct 2024 10:18:20 GMT

title: 探索與實作的融合〜將STEAM 精神融入兒童教學活動

Vaccination associated with gross domestic product and fewer deaths in countries and regions A verification study

Mon, 11 Dec 2023 06:02:58 GMT

title: Vaccination associated with gross domestic product and fewer deaths in countries and regions A verification study abstract: Background: Vaccination can have a substantial impact on mitigating COVID-19 outbreaks. However, the vaccine rollout rates associated with the gross domestic product (GDP) and few deaths are required for verification. Three hypotheses were made: 1. the inflection point (IP) days on the cumulative number of confirmed cases (CNCCs) in 2021 are improved (i.e., shorter than 2021); 2. the vaccinations are associated with national GDP and fewer deaths; and 3. the association is weak between vaccinations and CNCC IP based on the argument that vaccinations are limited to protection against milder infection. Methods: The corresponding CNCCs and deaths were downloaded from the GitHub website. Four variables, including IP days on CNCCs and deaths, GDP per capita, and vaccine doses administered per 100 people (VD100) in countries/regions, were collected. Correlation coefficients (CCs) between variables were computed to verify the association with vaccination rates. Four tasks were achieved: 1. determining IP days for each country/region; 2. drawing forest plots to identify the improvement in 2021; 3. using a pyramid plot to identify the improvement in US states; and 4. applying the Kano diagram to verify the three hypotheses mentioned above. Results: We observed that 1. the IP days on CNCCs in 2021 were shorter than those in 2021 among continents and US states; 2. the CCs were 0.66 ( = 12.21, < .01) and -0.15 ( = 2.11, < .01) using the paired variables of [VD100, GDP] and [VD100, deaths IP], respectively; and 3. tPtPthe CC between CNCC IP and deaths IP was 0.73 ( = 14.84, < .01), but a weak association with CC = -0.01 existed between CNCC IP and VD100. Conclusion: Our results indicate that vaccination has a significant effect on mitigating COVID-19 outbreaks, even with limited protection against infection. Continued compliance with nonpharmaceutical interventions is essential to the fight against COVID-19 in the future.

Using the forest plot to compare citation achievements in bibliographic and meta-analysis studies since 2011 using data on PubMed Central: A retrospective study

Mon, 11 Dec 2023 06:02:29 GMT

title: Using the forest plot to compare citation achievements in bibliographic and meta-analysis studies since 2011 using data on PubMed Central: A retrospective study abstract: Background: We saw a steady increase in the number of bibliographic studies published over the years. The reason for this rise is attributed to the better accessibility of bibliographic data and software packages that specialize in bibliographic analyses. Any difference in citation achievements between bibliographic and meta-analysis studies observed so far need to be verified. In this study, we aimed to identify the frequently observed MeSH terms in these 2 types of study and investigate whether the highlighted MeSH terms are strongly associated with one of the study types. Methods: By searching the PubMed Central database, 5121 articles relevant to bibliometric and meta-analysis studies were downloaded since 2011. Social network analysis was applied to highlight the major MeSH terms of quantitative and statistical methods in these 2 types of studies. MeSH terms were then individually tested for any differences in event counts over the years between study types using odds of 95% confidence intervals for comparison. Results: In these 2 studies, we found that the most productive countries were the United States (19.9%), followed by the United Kingdom (8.8%) and China (8.7%); the most number of articles were published in PLoS One (2.9%), Stat Med (2.5%), and Res Synth (2.4%); and the most frequently observed MeSH terms were statistics and numerical data in bibliographic studies and methods in meta-analysis. Differences were found when compared to the event counts and the citation achievements in these 2 study types. Conclusion: The breakthrough was made by developing a dashboard using forest plots to display the difference in event counts. The visualization of the observed MeSH terms could be replicated for future academic pursuits and applications in other disciplines using the odds of 95% confidence intervals.