Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/521
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 17333/19639 (88%)
造訪人次 : 5442315      線上人數 : 346
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋
    請使用永久網址來引用或連結此文件: http://ir.cnu.edu.tw/handle/310902800/521


    標題: 中草藥化粧品原料之開發與應用 (II)
    作者: 丁秀玉
    貢獻者: 化粧品科技研究所
    關鍵字: 牡丹皮
    抗自由基
    酪氨酸酶抑制劑
    Mudanpi
    free radical scanvenger
    tyrosinase inhibitor
    日期: 2006
    上傳時間: 2008-05-19 13:37:31 (UTC+8)
    出版者: 台南縣:嘉南藥理科技大學化粧品科技研究所
    摘要: 中藥牡丹皮 (Paeonia suffruticosa Andr.) 以生物活性指標導引純化分離有效成分,其結果得到具有掃除自由基DPPH的成分為2,5-Dihydroxy-4-methylacetophenone (1)、2,5-Dihydroxy-4-methoxyacetophenone (2)、Methyl gallate (4) 、Benzoic acid (5)、4-Hydroxy-3-methoxybenzoic acid (6)、Ethyl gallate (7) 、p-Hydroxybenzoic acid (8)及Gallic acid (9) 和抑制酪氨酸酶活性的成分為3-Hydroxy-4-methoxyacetophenone (3) 、Benzoic acid (5) 、Ethyl gallate (7) 及p-Hydroxybenzoic acid (8)。分離出化合物中4和7為首次自此植物中分離得到。化合物1、2、5和6為首次發現其具有將其應用在掃除自由基DPPH,化合物3、7和8為首次發現其具有抑制酪氨酸酶之活性。上述有效成分之化合物是經由光譜分析而確定其化學結構,
    Chinese herb” Mudanpi “ (root cortex of Paeonia suffruticosa Andr.) has been described to possess cosmetic activity in tradition Chinese medicine. The bioassay guided purification to get nine compounds. Among of isolated compounds, 2,5-Dihydroxy-4-methylacetophenone (1), 2,5-Dihydroxy-4-methoxyacetophenone (2), Methyl gallate (4), Benzoic acid (5), 4-Hydroxy-3-methoxybenzoic acid (6), Ethyl gallate (7), p-Hydroxybenzoic acid (8), and Gallic acid (9) show DPPH scavenging activity and 3-Hydroxy-4-methoxyacetophenone (3), Benzoic acid (5), Ethyl gallate (7), and p-Hydroxybenzoic acid (8) inhibit tyrosinase activity. Among the purified compounds, 4 and 7 were the first purified from plant; 1, 2, 5, and 6 were first identified with DPPH scavenging activity; 3, 7, and 8 were first identified as tyrosinase inhibitors. Their structures have been established on the basis of spectral evidences.
    關聯: 計畫編號 : CNIC9505
    顯示於類別:[化妝品應用與管理系(所)] 校內計畫

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    95CNIC9505.pdf172KbAdobe PDF1271檢視/開啟


    在CNU IR中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋