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    請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/34589


    標題: A Population-Based Study of Social Demographic Factors, Associated Diseases and Recurrent Corneal Erosion in Taiwan
    作者: Jan, Ren-Long
    Ho, Chung-Han
    Wang, Jhi-Joung
    Tseng, Sung-Huei
    Chang, Yuh-Shin
    貢獻者: Chang Jung Christian University
    Chi Mei Hospital
    Chia Nan University of Pharmacy & Science
    Chi Mei Hospital
    Chi Mei Hospital
    Southern Taiwan University of Science & Technology
    National Cheng Kung University
    National Cheng Kung University Hospital
    Chi Mei Hospital
    關鍵字: eosinophil cationic protein
    confocal microscopy
    tears
    deposition
    日期: 2022
    上傳時間: 2023-12-11 13:59:23 (UTC+8)
    出版者: FRONTIERS MEDIA SA
    摘要: PurposeTo investigate the association of recurrent corneal erosion (RCE) with sociodemographic factors and associated ocular conditions or systemic diseases. MethodsThis nationwide, population-based, retrospective, matched case-controlled study included 98,895 RCE patients, identified by the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) code 371.42, were selected from the Taiwan National Health Insurance Research Database. The age-, sex-, and index date- matched control group included 98,895 non-RCE control group also selected from the Taiwan Longitudinal Health Insurance Database 2000. Sociodemographic factors and associated ocular conditions or systemic diseases were examined using univariate logistic regression analyses, and continuous variables were analyzed using paired t-test. The odds ratio (OR) of developing RCE were compared using adjusted logistic regression analysis. ResultsPatients with ocular conditions including corneal abrasion, ocular allergic conditions, and corneal dystrophy were more likely to have RCE than the control group (adjusted OR = 63.56, 95% CI = 42.06-96.06, p < 0.0001; adjusted OR = 24.27, 95% CI = 20.51-28.72, p < 0.0001; adjusted OR = 17.10, 95% CI = 5.14-59.93, p < 0.0001, respectively). Patients with systemic diseases such as diabetes mellitus, hyperlipidaemia, and atopy trait have significantly higher ORs for RCE development. Patients residing in either Northern Taiwan or a metropolis city had higher odds of developing RCE; however, there were no significant differences in income or occupation on the probability to develop RCE. ConclusionRCE is strongly associated with corneal abrasion, ocular allergic conditions, corneal dystrophy, diabetes mellitus, hyperlipidaemia, and atopy trait.
    關聯: FRONTIERS IN PUBLIC HEALTH, v.10, n.CB2, pp.CC2, pp.-,
    顯示於類別:[行政單位] 123

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