Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/34522
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    標題: Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome
    作者: Tsai, Wan-Hua
    Chou, Chia-Hsuan
    Chiang, Ying-Ju
    Lin, Ching-Gong
    Lee, Che-Hsin
    貢獻者: GenMt Biotech Inc, Res & Dev Dept
    Chia Nan Univ Pharm & Sci, Dept Cosmet Sci
    Natl Sun Yat Sen Univ, Dept Biol Sci
    China Med Univ, China Med Univ Hosp, Dept Med Res
    Kaohsiung Med Univ, Dept Med Lab Sci & Biotechnol
    關鍵字: Lactobacillus plantarum-GMNL6
    probiotics
    skirt care
    care products
    日期: 2021
    上傳時間: 2023-11-11 12:00:48 (UTC+8)
    出版者: IVYSPRING INT PUBL
    摘要: Bacteria response to their environment by producing some compounds which are used in cosmetic and pharmaceutical applications. Some probiotics can regulate immune response and modulate the symptoms of several diseases. Bacteria affect skin response to skin care products. Bacteria are thought to play an important role in acne incidence, skin moisture, and nutrient metabolism, but only a few studies have focused on the extracts of Lactobacillus plantarum in skin care. In this study, we identified that L. plantarum-GMNL6 enhanced collagen synthesis and the gene expression of serine palmitoyltransferase small subunit A. Meanwhile, L. plantarum-GMNL6 reduced the melanin synthesis, the biofilm of Staphylococcus aureus, and the proliferation of Cutibacterium acnes. Information from clinical observation during the ointment for external face use in people displayed that the syndromes of skin moisture, skin color, spots, wrinkles, UV spots, and porphyrins were improved. The diversification of human skin microbiomes was affected by smearing the face of volunteers with L. plantarum-GMNL6. Understanding the potential mechanisms of the action of L. plantarum-GMNL6 in dermatologic conditions promotes the development of care products.
    關聯: INT J MED SCI, v.18, n.5, pp.1114-1120
    显示于类别:[化妝品應用與管理系(所)] 期刊論文

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