Effects of Chinese and Western Medicine on Patients with Dengue Fever

doi:10.1142/S0192415X20500160

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Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/34140

Title:	Effects of Chinese and Western Medicine on Patients with Dengue Fever
Authors:	Chen, Yu-Pei Ho, Tzong-Shiann Lee, Po-Chang Chang, Hen-Hong Shieh, Gia-Shing Lee, Chih-, I Hu, Wen-Long Hung, Yu-Chiang
Contributors:	Minist Hlth & Welf, Tainan Hosp, Dept Chinese Med Minist Hlth & Welf, Tainan Hosp, Dept Urol Minist Hlth & Welf, Tainan Hosp, Dept Infect Natl Cheng Kung Univ, Coll Med Natl Cheng Kung Univ, Coll Med, Dept Biochem & Mol Biol Natl Cheng Kung Univ Hosp, Dept Pediat Chia Nan Univ Pharm & Sci, Dept Pharm Minist Hlth & Welf, Natl Hlth Insurance Adm China Med Univ, Coll Chinese Med, Sch Chinese Med China Med Univ, Coll Chinese Med, Grad Inst Integrated Med China Med Univ, Coll Chinese Med, Chinese Med Res Ctr China Med Univ Hosp, Dept Chinese Med Chang Gung Univ, Coll Med, Kaohsiung Chang Gung Mem Hosp, Dept Chinese Med Chang Gung Univ, Coll Med, Sch Tradit Chinese Med Kaohsiung Med Univ, Coll Med Fooyin Univ, Coll Nursing
Keywords:	Traditional Chinese Medicine Dengue Fever Chinese Herb Clinical Study
Date:	2020
Issue Date:	2022-11-18 11:25:41 (UTC+8)
Publisher:	World Scientific Publ Co Pte Ltd
Abstract:	Dengue fever is an important epidemic disease with a high prevalence in tropical and subtropical countries. We aimed to investigate the effects of a treatment integrating traditional Chinese (TCM) and Western medicines on dengue inpatients with warning signs (i.e., group B) according to the World Health Organization dengue classification in this retrospective cohort study of medical records. Inpatients who were treated with conventional Western therapies in the absence or presence of TCM were assigned to the control and treatment groups, respectively. Data were compared using an analysis of variance, general linear analysis, and chi-square test. The most common clinical symptoms and signs of dengue fever were fever and muscle ache. The treatment group patients were significantly more likely to present general weakness and poor appetite than the control group patients. Patients in the treatment group were more likely to experience stomachache than those in the control group. Moreover, comparisons of the changes in hemoglobin and alanine aminotransferase levels over time revealed significant differences between the patient groups. Zhu Ye Shi Gao Tang, Gui Pi Tang, Paeonia suffruticosa, and Clerodendrum cyrtophyllum were the most commonly administered TCM formula and single herbs in this study. Patients in the treatment group experienced a resolution of symptoms, signs, and laboratory data and were discharged smoothly, without deterioration to death or critical care. Our findings suggest that the integration of TCM and Western medicine may yield an appropriate treatment for dengue fever.
Relation:	American Journal of Chinese Medicine, v.48, n.2, pp.12
Appears in Collections:	[Dept. of Pharmacy] Periodical Articles

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