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| 標題: | Effect of compression fracture on trabecular bone score at lumbar spine |
| 作者: | Hsu, Y.
Hsieh, T. -J.
Ho, C. -H.
Lin, C. -H.
Chen, C. K. -H. |
| 貢獻者: | Chi Mei Med Ctr, Dept Med Imaging
Kaohsiung Med Univ, Fac Med, Dept Radiol, Coll Med
Chi Mei Med Ctr, Dept Med Res
Chia Nan Univ Pharm & Sci, Dept Hosp & Hlth Care Management |
| 關鍵字: | Bone mineral density
Compression fracture
Dual-energy X-ray absorptiometry
Osteoporosis
Trabecular bone scores |
| 日期: | 2021 |
| 上傳時間: | 2022-11-18 11:25:35 (UTC+8) |
| 出版者: | Springer London Ltd |
| 摘要: | Bone mineral density (BMD) may be increased due to vertebral compression fractures (VCF). Our study showed trabecular bone scores (TBS) was less affected than BMD by fractured vertebrae. The TBS of most compression fractures, including old and recent VCF with mild or moderate deformity and old VCF with severe deformity, could still be used in predicting fracture risk. Introduction Trabecular bone score (TBS), a noninvasive tool estimating bone microarchitecture, provides complementary information to lumbar spine bone mineral density (BMD). Lumbar spine BMD might be increased due to both degenerative disease and vertebral compression fractures (VCF). Lumbar spine TBS has been confirmed not influenced by osteoarthrosis, but the effects of VCF are still not been well evaluated. This study aimed to investigate whether lumbar spine TBS was affected by fractured vertebrae. Methods We studied postmenopausal women and men above 50 years old who underwent DXA between January 1, 2017, and May 31, 2019. By calculating the difference of BMD and TBS between L1 and the mean of L2-3, the study compared the difference of values between the control group and fracture group to determine the effects of fractured vertebrae on BMD and TBS. Results A total of 377 participants were enrolled with 202 in the control group (157 females; age: 68.06 +/- 6.47 years) and 175 in the fracture group (147 females; age: 71.71 +/- 9.44 years). The mean BMD of the L1 vertebrae in the fracture group was significantly higher than that in the control group (p < 0.0001). There was no significant difference between the mean differences of TBS between L1 and the means of L2-3 vertebrae in the control group and the most compression fractures, including old and recent VCF with mild or moderate deformity and old VCF with severe deformity. Conclusion Lumbar spine TBS, unlike BMD, is less affected by fractured vertebrae. The TBS of most compression fractures, including old and recent VCF with mild or moderate deformity and old VCF with severe deformity, could still be used in predicting fracture risk. |
| 關聯: | Osteoporosis International, v.32, n.5, pp.10 |
| 顯示於類別: | [化妝品應用與管理系(所)] 期刊論文
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