Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/33639
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    CNU IR > Pharmacy and Science > 2017 >  Item 310902800/33639
    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/33639


    Title: Calcium chloride 添加量對 Sodium Alginate/Aspirin/Calcium chloride/Polyglutamic acid 藥物
    Authors: 鄭莉渟
    鍾佳伶
    林彰泰
    劉孟春
    Contributors: 醫藥化學系
    化粧品應用及管理系
    Date: 2017
    Issue Date: 2022-01-25 14:59:07 (UTC+8)
    Abstract: 本研究將不同比例之阿斯匹靈(Asp) / 聚麩胺酸(γ-PGA) /海藻酸鈉(SA),加入不同濃度的氯化鈣溶液中,是為了獲得不同特性的顆粒,如顆粒大小、比表面積、表面型態、藥物包埋率,進而影響藥物的釋放擴散及釋放速率。本實驗原理為氯化鈣溶液中的鈣離子(Ca2+)會取代鈉離子(Na+)的角色,並且抓住海藻酸鈉分子間的羧酸離子,使得分子間的聯結性更強,利用此交聯作用(cross-linking)可使分子更為固定,並降低其流動性來形成顆粒。
    Relation: 2017 第十一屆嘉南藥理大學藥理學院師生研究成果發表會,起迄日:2017/05/02-2017/05/04
    Appears in Collections:[Pharmacy and Science] 2017
    [Dept. of Pharmacy] Proceedings

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