English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 18034/20233 (89%)
造訪人次 : 23364651      線上人數 : 492
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋
    請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/32681


    標題: Depression is a major risk factor for the development of dementia in people with lower urinary tract symptoms: A nationwide population-based study
    作者: Ou, Ming-Jung
    Huang, Chun-Che
    Wang, Yi-Chi
    Chen, Yung-Liang
    Chung-Han Ho(何宗翰)
    Wu, Ming-Ping
    Huang, Yu-Tung
    Wu, Chien-Yi
    Chen, Ping-Jen
    貢獻者: Kaohsiung Med Univ, Dept Family Med, Kaohsiung Med Univ Hosp
    Taichung Vet Gen Hosp, Dept Med Res
    Kaohsiung Med Univ, Dept Family Med, Kaohsiung Municipal Hsiao Kang Hosp
    Kaohsiung Med Univ, Dept Family Med, Kaohsiung Municipal Ta Tung Hosp
    Chi Mei Med Ctr, Dept Med Res
    Chia Nan Univ Pharm & Sci, Dept Hosp & Hlth Care Adm
    Chi Mei Fdn Hosp, Div Urogynecol, Dept Obstet & Gynecol
    Fu Jan Catholic Univ, Dept Obstet & Gynecol, Coll Med
    Chang Gung Mem Hosp, Ctr Big Data Analyt & Stat
    Kaohsiung Med Univ, Sch Med, Coll Med
    UCL, Marie Curie Palliat Care Res Dept, Div Psychiat
    Chi Mei Med Ctr, Palliat Care Ctr
    關鍵字: QUALITY-OF-LIFE
    WORK PRODUCTIVITY
    HEALTH
    MEN
    SEVERITY
    BURDEN
    IMPACT
    INCONTINENCE
    PREVALENCE
    SEXUALITY
    日期: 2019
    上傳時間: 2020-07-29 13:55:04 (UTC+8)
    出版者: PUBLIC LIBRARY SCIENCE
    摘要: Background/Objectives Studies have shown a strong relationship between depression and dementia. Lower urinary tract symptoms (LUTS) were reported to be independently associated with depression and dementia. However, the relationship between depression and cognitive dysfunction in patients with LUTS is not well characterized. Method We conducted a matched cohort study by using a one-million population-based dataset in Taiwan. A total of 15,944 patients with LUTS aged 50 or older were included from 2001 to 2005 and followed up until their death or the end of 2012. During the follow-up period, 1958 cases developed depression subsequently and were defined as the study group. 7832 patients without depression were then identified as control group, matching by age, gender, insurance premium, status of catastrophic illness certificate, and the index year in a 1: 4 ratio. The primary outcome was the onset of dementia. LUTS, depression, dementia, and other comorbidities were defined by the International Classification of Disease, 9th Revision, Clinical Modification coding system. Cox hazards models and Aalen Johansen curves were applied to measure the influence of depression on the risk of dementia in patients with LUTS. Results The crude incidence of depression among people with LUTS was 12.3%. The incidence of dementia in the depression group was significantly higher than that in the control group (12.2% versus 8.9%; P < 0.001). Depression was associated with a significantly greater risk of subsequent dementia after adjusted for socioeconomic status, number of outpatient visits and multiple comorbidities (adjusted hazard ratio: 1.32; 95% confidence interval: 1.131.54). Conclusions Depression is a major risk factor for the onset of subsequent dementia in patients with LUTS. Early screening and interventions for depression in patients with LUTS may be important to maintain cognitive function.
    關聯: Plos One, v.14, n.6, e0217984
    顯示於類別:[醫務管理系(所)] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    10.1371-journal.pone.0217984.pdf935KbAdobe PDF240檢視/開啟
    index.html0KbHTML800檢視/開啟


    在CNU IR中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋