Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/32325
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    Title: Apoptotic and Nonapoptotic Activities of Pterostilbene against Cancer
    Authors: Chen, Rong-Jane
    Kuo, Hsiao-Che
    Cheng, Li-Hsin
    Lee, Yu-Hsuan
    Chang, Wen-Tsan
    Wang, Bour-Jr
    Wang, Ying-Jan
    Cheng, Hung-Chi
    Contributors: Natl Cheng Kung Univ, Dept Food Safety Hyg & Risk Management, Coll Med
    Natl Cheng Kung Univ, Dept Biochem & Mol Biol, Coll Med
    Natl Cheng Kung Univ, Inst Basic Med Sci, Coll Med
    Natl Cheng Kung Univ, Dept Environm & Occupat Hlth, Coll Med
    Natl Cheng Kung Univ Hosp, Dept Occupat & Environm Med
    Chia Nan Univ Pharm & Sci, Dept Cosmet Sci
    Chia Nan Univ Pharm & Sci, Inst Cosmet Sci
    Taipei Med Univ, Grad Inst Clin Med, Coll Med [Wang, Ying-Jan
    China Med Univ, China Med Univ Hosp, Dept Med Res
    Asia Univ, Dept Biomed Informat
    Keywords: apoptosis
    fibronectin
    cancer metastasis
    pterostilbene
    Date: 2018-01
    Issue Date: 2019-12-16 09:35:44 (UTC+8)
    Publisher: MDPI
    Abstract: Cancer is a major cause of death. The outcomes of current therapeutic strategies against cancer often ironically lead to even increased mortality due to the subsequent drug resistance and to metastatic recurrence. Alternative medicines are thus urgently needed. Cumulative evidence has pointed out that pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene, PS) has excellent pharmacological benefits for the prevention and treatment for various types of cancer in their different stages of progression by evoking apoptotic or nonapoptotic anti-cancer activities. In this review article, we first update current knowledge regarding tumor progression toward accomplishment of metastasis. Subsequently, we review current literature regarding the anti-cancer activities of PS. Finally, we provide future perspectives to clinically utilize PS as novel cancer therapeutic remedies. We, therefore, conclude and propose that PS is one ideal alternative medicine to be administered in the diet as a nutritional supplement.
    ???metadata.dc.relation.uri???: http://dx.doi.org/10.3390/ijms19010287
    Relation: International Journal of Molecular Sciences, v.19, n.1, 287
    Appears in Collections:[Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles

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