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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/32325

    標題: Apoptotic and Nonapoptotic Activities of Pterostilbene against Cancer
    作者: Chen, Rong-Jane
    Kuo, Hsiao-Che
    Cheng, Li-Hsin
    Lee, Yu-Hsuan
    Chang, Wen-Tsan
    Wang, Bour-Jr
    Wang, Ying-Jan
    Cheng, Hung-Chi
    貢獻者: Natl Cheng Kung Univ, Dept Food Safety Hyg & Risk Management, Coll Med
    Natl Cheng Kung Univ, Dept Biochem & Mol Biol, Coll Med
    Natl Cheng Kung Univ, Inst Basic Med Sci, Coll Med
    Natl Cheng Kung Univ, Dept Environm & Occupat Hlth, Coll Med
    Natl Cheng Kung Univ Hosp, Dept Occupat & Environm Med
    Chia Nan Univ Pharm & Sci, Dept Cosmet Sci
    Chia Nan Univ Pharm & Sci, Inst Cosmet Sci
    Taipei Med Univ, Grad Inst Clin Med, Coll Med [Wang, Ying-Jan
    China Med Univ, China Med Univ Hosp, Dept Med Res
    Asia Univ, Dept Biomed Informat
    關鍵字: apoptosis
    cancer metastasis
    日期: 2018-01
    上傳時間: 2019-12-16 09:35:44 (UTC+8)
    出版者: MDPI
    摘要: Cancer is a major cause of death. The outcomes of current therapeutic strategies against cancer often ironically lead to even increased mortality due to the subsequent drug resistance and to metastatic recurrence. Alternative medicines are thus urgently needed. Cumulative evidence has pointed out that pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene, PS) has excellent pharmacological benefits for the prevention and treatment for various types of cancer in their different stages of progression by evoking apoptotic or nonapoptotic anti-cancer activities. In this review article, we first update current knowledge regarding tumor progression toward accomplishment of metastasis. Subsequently, we review current literature regarding the anti-cancer activities of PS. Finally, we provide future perspectives to clinically utilize PS as novel cancer therapeutic remedies. We, therefore, conclude and propose that PS is one ideal alternative medicine to be administered in the diet as a nutritional supplement.
    link: http://dx.doi.org/10.3390/ijms19010287
    關聯: International Journal of Molecular Sciences, v.19, n.1, 287
    Appears in Collections:[化妝品應用與管理系(所)] 期刊論文

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