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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/32292

    標題: Isocapnic buffering phase: a useful indicator of exercise endurance in patients with coronary artery disease
    作者: Yen, Yun-Shan
    Su, Daniel Chiung Jui
    Yuan, Kuo-Shu
    Chen, Po-Wei
    Chow, Julie Chi
    Chou, Willy
    貢獻者: Chi Mei Med Ctr, Dept Phys Med & Rehabil
    Natl Sun Yat Sen Univ, Dept Business Management
    Chi Mei Med Ctr, Dept Pediat
    Chia Nan Univ Pharm & Sci, Dept Recreat & Healthcare Management
    Chia Nan Univ Pharm & Sci, Inst Recreat Ind Management
    關鍵字: Isocapnic buffering phase
    cardiopulmonary exercise test
    cardiopulmonary function
    endurance performance
    coronary artery disease
    日期: 2018
    上傳時間: 2019-11-15 15:48:24 (UTC+8)
    摘要: Objectives: The significance of the isocapnic buffering (IB) phase - the period between the first ventilatory threshold (1st VT) and respiratory compensation point (RCP) - has not been adequately established in patients. This study aimed to determine the clinical significance of the IB phase in patients with coronary artery disease (CAD). Methods: This retrospective study included data of sixty-two CAD patients after coronary artery bypass graft (CABG) or percutaneous coronary intervention (PCI) performed in a single medical center between 2010 - 2014. According to their physical conditions, the patients performed incremental cardiopulmonary exercise test (CPET) using a cycle ergometer by the ramp of 5-20 W/min. Correlations between the corrected IB phase duration and age, body mass index (BMI), left ventricular ejection fraction (LVEF), and CPET parameters were evaluated using Pearson correlation coefficients. Variables predicting peak oxygen consumption (VO2) were evaluated using multiple regression. Results: Peak VO2 (p < 0.001), VO2 at RCP (p < 0.001), Delta O-2/Delta WR slope (p < 0.001), maximal partial pressure of end tidal CO2 (PetCO(2)) (p = 0.0012), VE/VCO2 slope (p = 0.010), BMI (p = 0.012), and age (p = 0.017) were significantly correlated, whereas LVEF (p = 0.246) and VO2 at 1st VT (p = 0.179) were not significantly correlated with the corrected IB phase duration. In multiple regression analysis, the corrected IB phase duration, VO2 at 1st VT, and Delta O-2/Delta WR slope were significantly associated with peak VO2. Conclusion: The findings indicate that the IB phase duration is a useful indicator of peripheral cardiopulmonary function and endurance performance in CAD patients. These findings could assist the exercise prescription of cardiac rehabilitation for patients with CAD.
    link: http://dx.doi.org/10.1080/00913847.2018.1426967
    Appears in Collections:[休閒保健管理系(所)] 期刊論文

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