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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/32263


    標題: Transcriptional responses of Acropora hyacinthus embryo under the benzo(a)pyrene stress by deep sequencing
    作者: Xiao, Rong
    Zhou, Hailong
    Chen, Chien-Min
    Cheng, Huamin
    Li, Hongwu
    Xie, Jia
    Zhao, Hongwei
    Han, Qian
    Diao, Xiaoping
    貢獻者: Hainan Univ, State Key Lab Marine Resource Utilizat South Chin
    Hainan Univ, Inst Trop Agr & Forestry
    Hainan Univ, Coll Ocean
    Chia Nan Univ Pharm & Sci, Dept Environm Resources Management
    Hainan Normal Univ, Key Lab Trop Isl Ecol, Minist Educ
    關鍵字: Acropora hyacinthus embryo
    Benzo(a)pyrene
    Deep sequencing
    Simple Sequence Repeats
    Single nucleotide Polymorphisms
    日期: 2018-09
    上傳時間: 2019-11-15 15:47:19 (UTC+8)
    出版者: PERGAMON-ELSEVIER SCIENCE LTD
    摘要: Coral embryos are a critical and sensitive period for the early growth and development of coral. Benzo(a) pyrene (BaP) is widely distributed in the ocean and has strong toxicity, but there is little information on the toxic effects to coral embryos exposed to this widespread environmental contaminant. Thus, in this study, we utilized the Illumina Hiseg(TM) 4000 platform to explore the gene response of Acropora hyacinthus embryos under the BaP stress. A total of 130,042 Unigenes were obtained and analyzed, and approximately 37.67% of those matched with sequences from four different species. In total, 2606 Unigenes were up-regulated, and 3872 Unigenes were down-regulated. After Gene Ontology (GO) annotation, the results show that the "cellular process" and "metabolic process" were leading in the category of biological processes, which the "binding" and "catalytic activity" were the most abundant subcategories in molecular function. Based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, the most differentially expressed genes (DEGs) were enriched, as well as down-regulated in the pathways of oxidative phosphorylation, metabolism of xenobiotics, immune-related genes, apoptosis and human disease genes. At the same time, 388,197 of Single-nucleotide Polymorphisms (SNPs) and 6164 of Simple Sequence Repeats (SSRs) were obtained, which can be served as the richer and more valuable SSRs molecular markers in the future. The results of this study can help to better understand the toxicological mechanism of coral embryo exposed to BaP, and it is also essential for the protection and restoration of coral reef ecosystem in the future. (C) 2018 Elsevier Ltd. All rights reserved.
    link: http://dx.doi.org/10.1016/j.chemosphere.2018.04.149
    關聯: Clinical Science, v.206, pp.387-397
    Appears in Collections:[環境資源管理系(所)] 期刊論文

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