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    標題: One-Year Mortality of Patients with Chronic Kidney Disease After Spinal Cord Injury: A 14-Year Population-Based Study
    作者: Yu, Shou-Chun
    Kuo, Jinn-Rung
    Shiue, Yow-Ling
    Yu, Zong-Xing
    Ho, Chung-Han
    Wu, Chia-Chun
    Wang, Jhi-Joung
    Chu, Chin-Chen
    Lim, Sher-Wei
    貢獻者: Natl Sun Yat Sen Univ, Inst Biomed Sci
    Chi Mei Med Ctr, Chiali Branch, Dept Neurosurg
    Chi Mei Med Ctr, Chiali Branch, Dept Orthoped
    Chi Mei Med Ctr, Chiali Branch, Dept Med Res
    Chi Mei Med Ctr, Dept Nephrol
    Chi Mei Med Ctr, Dept Anesthesiol
    Min Hwei Coll Hlth Care Management, Dept Nursing
    Min Hwei Coll Hlth Care Management, Dept Dent Lab Technol
    Southern Taiwan Univ Sci & Technol, Dept Biotechnol
    Chia Nan Univ Pharm & Sci, Dept Pharm
    關鍵字: Chronic kidney disease
    End-stage renal disease
    Mortality
    Population-based study
    Spinal cord injury
    Taiwan
    日期: 2017-09
    上傳時間: 2018-11-30 15:57:12 (UTC+8)
    出版者: Elsevier Science Inc
    摘要: OBJECTIVE: Chronic kidney disease (CKD) has become a global public health burden because of its increasing incidence, high risk of progression to end-stage renal disease (ESRD), and poor prognosis. We aimed to investigate the 1-year mortality of patients with spinal cord injury (SCI) with CKD and ESRD, and compare it with that of patients with SCI without CKD by reviewing a large Taiwanese population data set. METHODS: In this 14-year retrospective cohort study, the study group (SCI with CKD group, n = 3315) and comparison group (SCI without CKD group, n = 6630) were matched at a 1: 2 ratio with propensity score matching by age, sex, comorbidities, length of intensive care unit stay, and length of stay. The 1-year mortality and the relative risks of mortality were calculated. Mortality stratified by age, sex, and comorbidities was also analyzed. RESULTS: The SCI with CKD group had a significantly shorter survival period (10.13 vs. 10.97 months), higher 1-year mortality (17.65% vs. 8.54%), and higher risk of mortality than did the comparison group (adjusted hazard ratio, 2.25). Furthermore, patients with CKD with ESRD had a 7.71-fold higher risk of mortality than did patients with SCI without CKD for ages < 50 years. The presence of comorbidities was a risk factor for mortality among patients with SCI CKD or ESRD in contrast to patients with SCI without CKD. CONCLUSIONS: Patients with SCI with CKD, especially those with ESRD, have a higher risk of mortality than do patients who do not have CKD. Therefore, patients with CKD should have carefully monitoring for the development of 1-year mortality after SCI, especially for ESRD.
    關聯: World Neurosurgery, v.105, pp.462-469
    顯示於類別:[藥學系(所)] 期刊論文

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