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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/31795


    標題: Effect of liver cirrhosis on long-term outcomes after acute respiratory failure: A population-based study
    作者: Lai, Chih-Cheng
    Ho, Chung-Han
    Cheng, Kuo-Chen
    Chao, Chien-Ming
    Chen, Chin-Ming
    Chou, Willy
    貢獻者: Chi Mei Med Ctr, Dept Intens Care Med
    Chi Mei Med Ctr, Dept Med Res
    Chi Mei Med Ctr, Internal Med
    Chung Hwa Univ Med Technol, Dept Safety Hlth & Environm
    Chia Nan Univ Pharm & Sci, Dept Recreat & Hlth Care Management
    關鍵字: Liver cirrhosis
    Mechanical ventilation
    Outcome
    日期: 2017-03-28
    上傳時間: 2018-11-30 15:57:03 (UTC+8)
    出版者: Baishideng Publishing Group Inc
    摘要: AIM To assessed the effect of liver cirrhosis (LC) on the poorly understood long-term mortality risk after first-ever mechanical ventilation (1-MV) for acute respiratory failure. METHODS All patients in Taiwan given a 1-MV between 1997 and 2013 were identified in Taiwan's Longitudinal Health Insurance Database 2000. Each patient with LC was individually matched, using a propensity-score method, to two patients without LC. The primary outcome was death after a 1-MV. RESULTS A total of 16653 patients were enrolled: 5551 LC-positive (LC[Pos]) patients, including 1732 with cryptogenic LCs and 11102 LC-negative (LC[Neg]) controls. LC[Pos] patients had more organ failures and were more likely to be admitted to medical department than were LC[Neg] controls. LC[Pos] patients had a significantly lower survival rate (AHR = 1.38, 95%CI: 1.32- 1.44). Moreover, the mortality risk was significantly higher for patients with non-cryptogenic LC than for patients with cryptogenic LC (AHR = 1.43, 95%CI: 1.32- 1.54) and patients without LC (AHR = 1.56, 95%CI: 1.32- 1.54). However, there was no significant difference between patients with cryptogenic and without LC (HR = 1.05, 95% CI: 0.98- 1.12). CONCLUSION LC, especially non-cryptogenic LC, significantly increases the risk of death after a 1-MV.
    Appears in Collections:[休閒保健管理系(所)] 期刊論文

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