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https://ir.cnu.edu.tw/handle/310902800/31719
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| 標題: | Chemical composition and antioxidant, bactericidal, and matrix metalloproteinase inhibition activity of food-related plant |
| 作者: | Chen, Chin-Hui
Chang, Tsan-Chang
Chen, Shih-Ying
Hsu, Su-Jung
Huang, Hsiu-Wen
Lee, Ching-Kuo |
| 貢獻者: | Yuanpei Univ, Dept Hlth & Leisure Management
Mackay Jr Coll Med Nursing & Management, Dept Nursing
Chia Nan Univ Pharm & Sci, Dept Hlth & Nutr
Natl Chiayi Univ, Dept Food Sci
Taiwan Endem Species Res Inst, Chichi 552, Taiwan
Taipei Med Univ, Sch Pharm |
| 關鍵字: | Antioxidant
Antimicrobial
Matrix metalloproteinases
Rhodiola rosea
Ligusticum sinense
Chemical composition |
| 日期: | 2017-09-01 |
| 上傳時間: | 2018-11-30 15:54:07 (UTC+8) |
| 出版者: | Elsevier Science Bv |
| 摘要: | The present study aimed to investigate bio-function, focusing the on antioxidant, bactericidal, and matrix metalloproteinase (MMP) regulatory activity, of food-related plants. Bioassay-coupled chromatography and bioassay guiding, the rapid and simple screening method, was used to identify potential antioxidant and bactericidal components from fifty-five food-related plants. Lonicera japonica exhibited moderate xanthine oxidase (XO) inhibition and antioxidant activity. Rhodiola rosea, provoked strongly inhibition for tyrosinase, lipoxygenase (LOX), XO and MMP-2 activity. The organic fractions of Ligusticum sinense had a significant antimicrobial effect against two Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and two Gram-positive species (Staphylococcus aureus, and Bacillus subtilis). The chemical structures of MMP-2-inhibiting and antimicrobial components was further identified as 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside and ferulic acid, respectively, which were determined by H-1 and C-13 nuclear magnetic resonance (NMR) and mass spectrometry (MS). The results suggest that R. rosea and L. sinense could be a useful natural food preservatives and potential nutraceutical ingredients. (C) 2017 Elsevier Ltd. All rights reserved. |
| 關聯: | Lwt-Food Science and Technology, v.82, pp.411-419 |
| 顯示於類別: | [保健營養系(所) ] 期刊論文
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