Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/31681
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    標題: Acupuncture on Renal Function in Patients with Chronic Kidney Disease: A Single-Blinded, Randomized, Preliminary Controlled Study
    作者: Yu, Jung-Sheng
    Ho, Chung-Han
    Wang, Hsien-Yi
    Chen, Yung-Hsiang
    Hsieh, Ching-Liang
    貢獻者: China Med Univ, Coll Chinese Med, Grad Inst Integrated Med
    Chi Mei Med Ctr, Dept Chinese Med
    Chia Nan Univ Pharm & Sci, Dept Cosmet Sci
    Chi Mei Med Ctr, Dept Med Res
    Chia Nan Univ Pharm & Sci, Dept Pharm
    Chi Mei Med Ctr, Div Nephrol, Dept Med
    Chia Nan Univ Pharm & Sci, Dept Sports Management
    China Med Univ Hosp, Dept Chinese Med
    China Med Univ, Grad Inst Acupuncture Sci
    China Med Univ, Res Ctr Chinese Med & Acupuncture
    關鍵字: acupuncture treatment
    renal function
    chronic kidney disease
    日期: 2017-08
    上傳時間: 2018-11-30 15:52:40 (UTC+8)
    出版者: Mary Ann Liebert, Inc
    摘要: Objective: To evaluate the feasibility effect of acupuncture on renal function in patients with chronic kidney disease (CKD). Methods: In total, 59 patients with CKD were randomized into acupuncture (AG; n = 30) and sham acupuncture (CG; n = 29) treatment groups. In the AG, acupuncture was applied to bilateral Hegu (LI4), Zusanli (ST36), and Taixi (KI3) to obtain qi, and electroacupuncture (2 Hz) was applied to two acupoint pairs (right Zusanli and Taixi and left Zusanli and Taixi) once per week for 12 weeks. In the CG, the acupuncture methods were identical to in the AG, and the acupuncture needle was applied to the subcutaneous layer at 1.5 cm lateral to the aforementioned acupoints, without electrical discharge. The levels of serum creatinine and estimated glomerular filtration rate (eGFR) were measured at 3 months (observation period; O), immediately before the acupuncture treatment (baseline; B), at 12 weeks (after treatment completion; T12), and at the 3-month followup (postacupuncture treatment; P). Results: In total, 53 patients (AG, n = 28; CG, n = 25) with CKD completed the trial. The serum creatinine levels at baseline (B) were 1.45 mg/dL in the AG and 1.67 mg/dL in the CG (p = 0.1298). Furthermore, the change in serum creatinine levels after the acupuncture treatment (T12) was 1.41 mg/dL in the AG and 1.65 mg/ dL in the CG (p = 0.0489). The eGFR at baseline was 51.85 mL/min/1.73m(2) in the AG and 42.50 mL/min/ 1.73m(2) in the CG (p = 0.0855). The change in the eGFR after the acupuncture treatment was 54.50 mL/min/ 1.73m(2) in the AG and 43.60 mL/min/1.73m(2) in the CG (p = 0.0470). Conclusion: Acupuncture at bilateral Hegu, Zusanli, and Taixi for 12 weeks reduced creatinine levels and increased eGFR levels. The study only provided a feasibility method for the treatment of patients with CKD. However, the results of this preliminary study warrant further investigation.
    關聯: Journal of Alternative and Complementary Medicine, v.23, n.8, pp.624-631
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