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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/31675

    標題: Close correlation between the ankle-brachial index and symptoms of depression in hemodialysis patients
    作者: Jong, Ing-Chin
    Tsai, Hung-Bin
    Lin, Chien-Hung
    Ma, Tsung-Liang
    Guo, How-Ran
    Hung, Peir-Haur
    Hung, Kuan-Yu
    貢獻者: Ditmanson Med FdnChia Yi Christian Hosp, Dept Internal Med, Div Nephrol
    Natl Taiwan Univ Hosp, Dept Tramatol
    Natl Yang Ming Univ, Inst Clin Med
    Taipei City Hosp, Zhongxing Branch, Dept Pediat
    Natl Cheng Kung Univ, Dept Environm & Occupat Hlth, Med Coll
    Chia Nan Univ Pharm & Sci, Dept Appl Life Sci & Hlth
    Natl Taiwan Univ Hosp, Hsin Chu Branch, Dept Internal Med
    關鍵字: Ankle-brachial index
    Beck depression inventory
    日期: 2017-08
    上傳時間: 2018-11-30 15:52:28 (UTC+8)
    出版者: Springer
    摘要: As both of peripheral arterial disease (PAD) and depression carried a poor prognosis in patients on maintenance hemodialysis (MHD), we investigated the correlation between the ankle-brachial index (ABI), an indicator of subclinical PAD, and symptoms of depression in patients on MHD. One hundred and twenty-nine patients on MHD (75 males and 54 females, mean age 64.8 +/- 12 years) were enrolled in this cross-sectional study, which aimed at evaluating the relationship between symptoms of depression and ABI. Demographic as well as clinical and laboratory variables including status of diabetes, chronic hepatitis C infection, dialysis duration, Charlson comorbidity index (CCI), plasma levels of albumin, C-peptide, insulin, high-sensitive C-reactive protein (hsCRP), interleukin-6 (IL-6), adiponectin, and lipid profile were obtained. The self-administered beck depression inventory (BDI) was used to determine the presence or absence of symptoms of depression, and depression was defined as a BDI score ae 14. Multivariable-adjusted linear regression models were constructed to confirm the independent association of biologic parameters of symptoms of depression. Significance was defined as P < 0.05. Statistical analyses were performed using SPSS/Windows software (SPSS Science, v. 15.0, Chicago, IL). The mode of multivariate analysis showed that diabetes (beta = 3.594; P = 0.040), hepatitis C infection (beta = 4.057; P = 0.008), levels of serum albumin (beta = -5.656; P = 0.024), C-peptide (beta = -0.292; P = 0.002), ABI (beta = -9.041; P = 0.031), and Ln-transformed hsCRP were significantly associated with BDI. Hepatitis C infection, serum levels of albumin, C-peptide, and ABI levels were found to be correlated with BDI (P < 0.05).
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