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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/31607

    標題: Is insomnia a risk factor for new-onset asthma? A population-based study in Taiwan
    作者: Lin, Yu-Chieh
    Lai, Chih-Cheng
    Chien, Chih-Chiang
    Chen, Chin-Ming
    Chiang, Shyh-Ren
    Ho, Chung-Han
    Weng, Shih-Feng
    Cheng, Kuo-Chen
    貢獻者: Jiannren Hosp, Dept Family Med
    Chi Mei Med Ctr, Dept Intens Care Med
    Chi Mei Med Ctr, Dept Internal Med
    Chi Mei Med Ctr, Dept Intens Care Med
    Chia Nan Univ Pharm & Sci, Dept Recreat & Healthcare Management
    Chi Mei Med Ctr, Dept Med Res
    Chia Nan Univ Pharm & Sci, Dept Hosp & Hlth Care Adm
    Kaohsiung Med Univ, Dept Healthcare Adm & Med Informat
    Chung Hwa Univ Med Technol, Dept Safety Hlth & Environm Engn
    關鍵字: Sleep Duration
    Daytime Sleepiness
    日期: 2017-11
    上傳時間: 2018-11-30 15:50:01 (UTC+8)
    出版者: Bmj Publishing Group
    摘要: Objectives To determine whether insomnia at baseline is a risk factor for new-onset asthma. Methods We recruited 48 871 patients with insomnia (insomnia group) newly diagnosed between 2002 and 2007, and 97 742 matched controls without insomnia (control group) from Taiwan's Longitudinal Health Insurance Database 2000. All of the patients were followed up for 4 years to see whether new-onset asthma developed. Patients with previous asthma or insomnia were excluded. The Poisson regression was used to estimate the incidence rate ratios (IRRs) and 95% CIs of asthma. Cox proportional hazard regression was used to calculate the risk of asthma between the two groups. Results After a 4-year follow-up, 424 patients in the insomnia group and 409 in the control group developed asthma. The incidence rate of asthma was significantly higher in the insomnia group (22.01vs10.57 per 10 000 person-years). Patients with insomnia have a higher risk of developing new-onset asthma during the 4-year follow-up (HR: 2.08, 95% CI 1.82 to 2.39). The difference remained significant after adjustment (adjusted HR: 1.89, 95% CI 1.64 to 2.17). Conclusions This large population-based study suggests that insomnia at baseline is a risk factor for developing asthma.
    關聯: BMJ Open, v.7, n.11, e018714
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