Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/31226
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    CNU IR > Pharmacy and Science > 2015 >  Item 310902800/31226
    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/31226


    Title: 以超高壓液相層析法測定化妝品中防腐劑
    Authors: 陳瑩芸
    林維炤
    Contributors: 嘉南藥理大學化粧品應用與管理系
    Date: 2015-05-05
    Issue Date: 2018-03-27 10:38:39 (UTC+8)
    Abstract: 本研究主要目的同時且快速分離八種防腐劑,其中有Methyl 4-hydroxybenzoate (MP)、Ethyl 4-hydroxybenzoate(EP)、n-Propyl 4-hydroxybenzoate(PP)、Isopropyl p-hydroxybenzoate(IPP)、Butyl p-hydroxybenzoate(BP)、2-Phenylphenol(OPP)、2,4-Dichlorobenzyl alcohol(24CBM)、Chlorocresol(CC),以高效能液相層析(High-Performance Liquid Chromatography,HPLC)方式進行測定,並進行有機溶劑、有機修飾劑及稀釋溶劑之研究探討,由這些探討中找出最佳化條件極可能影響之參數。研究結果以等度條件(乙醇: 水= 35 : 65),偵測波長以254 nm、227 nm作梯度,樣品注射量5μL,流速為0.4mL/min,能達到最佳層析效果。以管柱C 18作為靜相,可有效分離八種防腐劑,且能獲得線性方程式相關係數(?2)均在0.999以上。且再自製樣品回收率90.58~109.72%
    Relation: 2015 第九屆嘉南藥理大學藥理學院師生研究成果發表會,起迄日:2015/05/05-2015/05/08,地點:嘉南藥理大學國際會議中心一樓
    Appears in Collections:[Pharmacy and Science] 2015

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