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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/31080

    標題: Clinical Significance of Community- and Healthcare-Acquired Carbapenem-Resistant Enterobacteriaceae Isolates
    作者: Tang, Hung-Jen
    Hsieh, Cheng-Fang
    Chang, Ping-Chin
    Chen, Jyh-Jou
    Lin, Yu-Hsiu
    Lai, Chih-Cheng
    Chao, Chien-Ming
    Chuang, Yin-Ching
    貢獻者: Chi Mei Med Ctr, Dept Med
    Chia Nan Univ Pharm & Sci, Dept Hlth & Nutr
    Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Dept Internal Med, Div Geriatr & Gerontol
    Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Dept Neurol
    Chi Mei Med Ctr, Dept Internal Med
    Chi Mei Med Ctr, Comm Infect Control
    Chi Mei Med Ctr, Dept Intens Care Med
    Min Hwei Coll Hlth Care Management, Dept Nursing
    Chi Mei Med Ctr, Dept Med Res
    關鍵字: nonsusceptible klebsiella-pneumoniae
    日期: 2016-03
    上傳時間: 2018-01-18 11:41:20 (UTC+8)
    出版者: Public Library Science
    摘要: This study was conducted to investigate the clinical significance, manifestations, microbiological characteristics and outcomes of carbapenem-resistant Enterobacteriaceae (wCRE) isolates, and compare the clinical features of community-and healthcare-acquired CRE isolates. A total of 78 patients were identified to have CRE. Klebsiella pneumoniae was the most common pathogens (n = 42, 53.8%), followed by Enterobacter cloacae (n = 24, 30.8%), and Escherichia coli (n = 11, 14.1%). Most of the patients acquired CRE from healthcare settings (n = 55, 70.5%), and other cases got CRE from community settings (n = 23, 29.5%). Nine cases (11.5%) were classified as CRE colonization. Among the remaining 69 cases of CRE infections, pneumonia (n = 28, 40.6%) was the most common type of infections, followed by urinary tract infection (n = 24, 34.8%), and intra-abdominal infection (n = 16, 23.2%). The patients acquired CRE from community settings were more likely to be elderly, female, and had more urinary tract infections than from healthcare settings. In contrast, the patients acquired CRE from healthcare settings had more intra-abdominal infections, intra-abdominal surgery, and presence of indwelling device than from community settings. In conclusion, community-acquired CRE are not rare, and their associated clinical presentations are different from healthcare-acquired CRE.
    關聯: Plos One, v.11 n.3, e0151897
    Appears in Collections:[保健營養系(所) ] 期刊論文

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