Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/31033
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 18034/20233 (89%)
造访人次 : 23351323      在线人数 : 445
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/31033


    標題: Morphology and opto-thermal properties of the thermo-responsive PNIPAAm-protected gold nanorods
    作者: Lee, Chia-Fen
    Zhang, Geng-Ming
    Nieh, Mu-Ping
    Don, Trong-Ming
    貢獻者: Chia Nan Univ Pharm & Sci, Inst Cosmet Sci, Dept Cosmet Sci
    Tamkang Univ, Dept Chem & Mat Engn
    Univ Connecticut, Inst Mat Sci, Polymer Program
    關鍵字: poly(N-isopropyl acrylamide)
    Gold nanorods
    Thermo-responsive
    Opto-thermal effect
    delivery
    日期: 2016-02
    上傳時間: 2018-01-18 11:40:16 (UTC+8)
    出版者: Elsevier Sci Ltd
    摘要: In this study, thermo-responsive poly(N-isopropyl acrylamide)-g-gold nanorods (PNIPAAm-g-GNRs) were prepared by grafting telechelic PNIPAAm-SH to the GNRs. They were stable in aqueous medium where the GNRs were protected by PNIPAAm chains as revealed by transmission electron microscope. The longitudinal surface plasmon absorbance had a red shift to 810 nm, and the lower critical solution temperature (LCST) of the PNIPAAm was increased to 34.9 degrees C. After being irradiated by near-IR for 5 min, the PNIPAAm-g-GNRs solution indicated a temperature increment above its LCST. The opto-thermal effect thus could induce the morphology change of the PNIPAAm, which was found to be reversible. Furthermore, the PNIPAAm-g-GNRs had a much lower cytotoxicity than the surfactant-stabilized GNRs. The cell viability of fibroblast after two days of culture could still reach 89.0% relative to the control. Therefore, the PNIPAAm-g-GNRs could be used as drug carriers in which the drug-release could be controlled by remote near-IR. (C) 2015 Elsevier Ltd. All rights reserved.
    關聯: Polymer, v.84, pp.138-147
    显示于类别:[化妝品應用與管理系(所)] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    31033.pdf2083KbAdobe PDF409检视/开启
    index.html0KbHTML1091检视/开启


    在CNU IR中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈