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    標題: Risk of Rhegmatogenous Retinal Detachment with Central Serous Chorioretinopathy
    作者: Chang, Yuh-Shin
    Chang, Chun
    Weng, Shih-Feng
    Wang, Jhi-Joung
    Jan, Ren-Long
    貢獻者: Chi Mei Med Ctr, Dept Ophthalmol
    Chang Jung Christian Univ, Grad Inst Med Sci, Coll Hlth Sci
    Univ Taipei, Dept Educ
    Chi Mei Med Ctr, Med Res
    Chia Nan Univ Pharm & Sci, Dept Hosp & Hlth Care Adm
    Chi Mei Med Ctr, Anesthesiol
    Chi Mei Med Ctr, Dept Pediat
    Natl Cheng Kung Univ, Grad Inst Clin Med
    關鍵字: central serous chorioretinopathy
    National Health Insurance Research Database
    population-based study
    rhegmatogenous retinal detachment
    日期: 2016-08
    上傳時間: 2018-01-18 11:38:51 (UTC+8)
    出版者: Lippincott Williams & Wilkins
    摘要: Purpose: To investigate the risk of rhegmatogenous retinal detachment (RRD) after central serous chorioretinopathy (CSCR). Methods: The study included 2,830 patients with CSCR and 16,980 control patients matched using a propensity score for age, sex, and comorbidities including status after cataract operation, blunt trauma, myopia, diabetes mellitus, hypertension, and hyperlipidemia from January 2001 through December 2010 from the Taiwan Longitudinal Health Insurance Database 2000. Information of each patient was collected until December 2011. Cox proportional hazard regression analysis was used to obtain the adjusted hazard ratio for RRD. The RRD-free survival rate was calculated using Kaplan-Meier analysis. Results: Thirty-five patients with CSCR (1.24%) and 27 controls (0.16%) had RRD (P < 0.0001) during follow-up, resulting in a significantly higher risk of RRD in the patients with CSCR (incidence rate ratio = 7.83, 95% confidence interval = 4.74-12.93). After adjustment for potential confounders, the adjusted hazard ratio for developing RRD was increased 7.85 times in the cohort of total sample (adjusted hazard ratio = 7.85, 95% confidence interval = 4.75-12.97). Conclusion: It was found that CSCR increased the risk of RRD even after adjustment for age, sex, and comorbidities including status after cataract operation, blunt trauma, myopia, diabetes mellitus, hypertension, and hyperlipidemia.
    關聯: Retina-The Journal of Retinal and Vitreous Diseases, v.36 n.8, pp.1446-1453
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