The preparation of Chitosn / Carboxymethyl Cellulose / TPP-Polyelectrolyte gle beads and its application on drug delivery system

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Title:	The preparation of Chitosn / Carboxymethyl Cellulose / TPP-Polyelectrolyte gle beads and its application on drug delivery system
Authors:	Mon Chun Liu Ming Zhou Chen Tsai-Yi Weng Chang Tay Lin
Contributors:	Chia Nan College of Pharmacy and Science Tainan
Keywords:	Chitosan Polyelectrolyte Complexation Carboxymethyl Cellulose T.Higuchi model.
Date:	2008-07
Issue Date:	2017-12-04 15:56:45 (UTC+8)
Abstract:	The purpose of this study was the preparation and characterization of drug containing polymer gel beads. Chitosan was dissolved with drug in 5 wt% acetic acid solution. Different chitosan gel beads were obtained by polyelectrolyte complexation with sodium salt of carboxymethyl cellulose and tripolyphosphate. The effect of drug entrap ratio, gel particle size, morphology and physical properties on drug released behavior were investigated. The results showed that the release rate was consistent with T. Higuchi model.
Relation:	第五屆海峽化學、生物及材料研討會，起迄日：2008/07/21-2008/07/22，地點：嘉南藥理科技大學
Appears in Collections:	[Pharmacy and Science] The 5rh Conference of Channel-bridge Chemistry, Biology and materal Science

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