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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/29719


    標題: Epidemiologic features and long-term outcome of dialysis patients with infective endocarditis in Taiwan
    作者: Chou, Ming-Ting
    Wang, Jhi-Joung
    Wu, Wen-Shiann
    Weng, Shih-Feng
    Ho, Chung-Han
    Lin, Zhe-Zhong
    Cheng, Tain-Junn
    Chien, Chih-Chiang
    關鍵字: Infective endocarditis
    Rheumatic heart disease
    Dialysis
    日期: 2015-01
    上傳時間: 2016-04-19 19:05:47 (UTC+8)
    出版者: Elsevier Ireland Ltd
    摘要: Background: The incidence of infective endocarditis (IE) is high in dialysis patients. Limited data are available on the risk factors for IE and long-term outcome after IE in dialysis patients, especially in Asian populations.
    Methods: We used Taiwan National Health Insurance Research Database to design a longitudinal cohort study. 68,426 ESRD patients who began dialysis between 1999 and 2007 were included. The follow-up period was from the start of dialysis to death, end of dialysis, or end of 2008. Cox proportional hazards models were used to identify the risk factors for IE.
    Results: IE was diagnosed in 502 patients during follow-up (201.4 per 100,000 person-years). Diabetes mellitus (DM), congestive heart failure (CHF), cerebro-vascular accident (CVA), and rheumatic heart disease (RHD) (HR: 3.07, 95% CI: 1.99-4.75) were associated with an increasing risk of development of IE. The cumulative incidence rate of IE in patients with RHD was 1.4, 2.2, and 3.9% at 1, 3, and 5 years. In-hospital mortality was 23.5%. Cumulative survival rates post-IE were 54.3% at 1 year and only 35.3% at 5 years.
    Conclusion: Dialysis patients had a higher risk of IE. Those who were older and had DM, CHF, CVA, or especially RHD were at a greater risk. Dialysis patients with IE also had high mortality
    關聯: International Journal of Cardiology, v.179, pp.465-469
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