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|標題: ||Epidemiologic features and long-term outcome of dialysis patients with infective endocarditis in Taiwan|
|作者: ||Chou, Ming-Ting|
|關鍵字: ||Infective endocarditis|
Rheumatic heart disease
|上傳時間: ||2016-04-19 19:05:47 (UTC+8)|
|出版者: ||Elsevier Ireland Ltd|
|摘要: ||Background: The incidence of infective endocarditis (IE) is high in dialysis patients. Limited data are available on the risk factors for IE and long-term outcome after IE in dialysis patients, especially in Asian populations.
Methods: We used Taiwan National Health Insurance Research Database to design a longitudinal cohort study. 68,426 ESRD patients who began dialysis between 1999 and 2007 were included. The follow-up period was from the start of dialysis to death, end of dialysis, or end of 2008. Cox proportional hazards models were used to identify the risk factors for IE.
Results: IE was diagnosed in 502 patients during follow-up (201.4 per 100,000 person-years). Diabetes mellitus (DM), congestive heart failure (CHF), cerebro-vascular accident (CVA), and rheumatic heart disease (RHD) (HR: 3.07, 95% CI: 1.99-4.75) were associated with an increasing risk of development of IE. The cumulative incidence rate of IE in patients with RHD was 1.4, 2.2, and 3.9% at 1, 3, and 5 years. In-hospital mortality was 23.5%. Cumulative survival rates post-IE were 54.3% at 1 year and only 35.3% at 5 years.
Conclusion: Dialysis patients had a higher risk of IE. Those who were older and had DM, CHF, CVA, or especially RHD were at a greater risk. Dialysis patients with IE also had high mortality
|Appears in Collections:||[職業安全衛生系(含防災所)] 期刊論文|
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