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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/29713


    標題: Manifestations of Perihepatic Lymph Nodes in Acute Flare of Chronic Hepatitis B: Association with HBeAg Status and with HBeAg Seroconversion
    作者: Ko, Yen-Ling
    Sun, Chi-Shu
    Chung, Kun-Ming
    Lin, Yu-Min
    Feng, I-Che
    Sheu, Ming-Jen
    Koay, Lok-Beng
    Lin, Ching-Yih
    Ho, Chung-Han
    Kuo, Hsing-Tao
    貢獻者: 醫務管理系
    老人服務事業管理系
    關鍵字: e-antigen seroconversion
    virus-infection
    abdominal lymphadenopathy
    hepatocellular-carcinoma
    antibody seroconversion
    acute exacerbations
    chinese patients
    natural-history
    liver-disease
    core antigen
    日期: 2015-02
    上傳時間: 2016-04-19 19:05:34 (UTC+8)
    出版者: Public Library Science
    摘要: It has been observed that enlargement of perihepatic lymph nodes may be seen in patients with chronic hepatitis B, particularly during acute flares of CHB. We hypothesized that there may be a correlation between the nodal change patterns in CHB patients with acute flare and HBeAg status. Perihepatic lymph node sizes of 87 patients with acute flares of CHB were documented, with a median follow up of 43 months. Patients were separated into 3 groups, HBeAg-positive with HBe seroconversion (group 1), HBeAg-positive without HBe seroconversion (group 2), and HBeAg-negative (group 3). Group 1 has the highest incidence of enlarged lymph nodes (92.3%) compared with group 2 (75.8%) and group 3 (46.8%) (p = 0.003). And if nodal width at acute flare was >8mm and interval change of nodal width was >3mm, the incidence of HBeAg seroconversion will be 75% (p<0.001).
    Conclusion
    Larger perihepatic lymph nodes are seen in CHB acute flare patients with positive HBeAg and the magnitude of nodal width change may predict HBeAg seroconversion at recovery.
    Appears in Collections:[老人服務事業管理系] 期刊論文
    [醫務管理系(所)] 期刊論文

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