Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/28607
English  |  正體中文  |  简体中文  |  Items with full text/Total items : 18034/20233 (89%)
Visitors : 23361072      Online Users : 585
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/28607


    Title: Insomnia Subtypes and the Subsequent Risks of Stroke Report From a Nationally Representative Cohort
    Authors: Wu, Ming-Ping
    Lin, Huey-Juan
    Weng, Shih-Feng
    Ho, Chung-Han
    Wang, Jhi-Joung
    Hsu, Ya-Wen
    Contributors: 通識教育中心
    化粧品應用與管理系
    醫務管理系
    Keywords: longitudinal studies
    sleep initiation and maintenance disorders
    stroke
    Date: 2014-05
    Issue Date: 2015-05-06 21:22:20 (UTC+8)
    Publisher: Lippincott Williams & Wilkins
    Abstract: Background and Purpose The studies assessing the impact of insomnia on stroke are still lacking. We aim to investigate insomnia in relation to subsequent stroke during the 4-year follow-up. Methods Data from the Taiwan National Health Insurance Research Database were used. Enrollees with International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis code for insomnia were compared with randomly selected, age- and sex-matched noninsomnia enrollees with subsequent hospitalization for stroke during the 4-year follow-up. All enrollees, insomniacs and noninsomniacs, did not have previous diagnosis of stroke, sleep apnea, and insomnia. Individuals with insomnia were further categorized into different subgroups based on their insomnia patterns to explore whether the risk of stroke varies by subtype. The risk of outcomes was assessed with Kaplan-Meier curves and the impact of insomnia was estimated using Poisson regression analysis and Cox proportional hazards models. Results The study included 21 438 (mean age, 5216 years) insomniacs and 64 314 matched noninsomniacs (mean age, 51 +/- 16 years). Compared with noninsomniacs, insomniacs had 54% higher risk of developing stroke (adjusted hazard ratio, 1.54; 95% confidence interval, 1.38-1.72). When breaking down into insomnia subgroups, the persistent insomniacs had a higher 3-year cumulative incidence rate of stroke than those in the remission group (P=0.024). The insomniacs-to-noninsomniacs incidence rate ratio for stroke was highest among those aged 18 to 34 years (incidence rate ratio, 8.06). Conclusions Insomnia predisposes individuals to increased risk of stroke and this association is profound among young adults. Our results underscore the clinical importance of identifying and treating insomnia. A novel behavioral intervention targeting insomnia that may prevent stroke should be explored.
    Relation: Stroke, v.45 n.5, pp.1349-1354
    Appears in Collections:[Dept. of Hospital and Health (including master's program)] Periodical Articles
    [Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles
    [The Center For General Education] Periodical Articles

    Files in This Item:

    File Description SizeFormat
    index.html0KbHTML1471View/Open


    All items in CNU IR are protected by copyright, with all rights reserved.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback