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    標題: Clinical characteristics of hyperglycemic crises in patients without a history of diabetes
    作者: Chou, Willy
    Chung, Min-Hsien
    Wang, Hsien-Yi
    Chen, Jiann-Hwa
    Chen, Wei-Lung
    Guo, How-Ran
    Lin, Hung-Jung
    Su, Shih-Bin
    Huang, Chien-Cheng
    Hsu, Chien-Chin
    貢獻者: 運動管理系
    休閒保健管理系
    關鍵字: Hyperglycemic crisis
    Mortality
    New-onset
    日期: 2014-11
    上傳時間: 2015-05-06 21:19:27 (UTC+8)
    出版者: Wiley-Blackwell
    摘要: Aims/IntroductionHyperglycemic crises without a history of diabetes have not been well studied. We compared the clinical characteristics of patients with and without a history of diabetes, and evaluated the glycated hemoglobin levels. Materials and MethodsConsecutive adult patients (aged >18years) visiting the emergency department (ED) between January 2004 and December 2010 were enrolled if they met the criteria for a hyperglycemic crisis. Patients were separated into those without and those with a history of diabetes. The 30-day mortality was the primary end-point. ResultsWe enrolled 295 patients who made 330 visits to the ED. Patients without a history of diabetes made up 24.5% (81/330) of the hyperglycemic crises. Patients without a history of diabetes were more prone than patients with a history of diabetes to be younger and male, and to have better consciousness and renal function, more significant diabetic signs and symptoms (e.g., thirst, polydipsia, polyuria and bodyweight loss), higher blood sugar, and less opportunity of infection and mortality. Most of the patients (93.8%, 76/81) had glycated hemoglobin of 6.5%. ConclusionsThe present study delineates the clinical characteristics of patients with hyperglycemic crises, but without a history of diabetes. Most patients had glycated hemoglobin 6.5%, which raises the argument of using this biomarker for routine screening of diabetes.
    關聯: Journal of Diabetes Investigation, v.5 n.6, pp.657-662
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