Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/28423
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 16812/19099 (88%)
造访人次 : 6427775      在线人数 : 60
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻


    標題: A Study of Cardiotoxic Principles From The Venom of Bungarus Fasc1Atus (Schneider)
    C. Y. LEE
    貢獻者: 私立嘉南藥學專科學校
    日期: 1975
    上傳時間: 2014-12-26 11:48:33 (UTC+8)
    摘要: It is well known that all of the elapid venoms contain neurotoxins which are the major principles causing death in animals. Neurotoxins of the venom of Bungarus fasciatus have?been isolated (GHOSH et al.,1939; MOORE and LOY, 1972; LIN SHAIU et al.,1972).In addition to neurotoxins, cobra venom also contains cardiotoxins which are responsible for the circulatory effects as well as for the local actions such as pain, edema and muscle degeneration?(LEE et al.,1968; LAI et., 1972). The venom of Binearus multicinctus contains no such cardictoxin-like principle and does not cause local actions. Although Bungarus fasciatus belongs to the same genus as Bungarus multicinctus, the venom of the former?causes local actions. Hence, it was considered that the venom of Bungarus fasciatus might contain cardiotoxin-like principles. The result described in this paper verified this hypothesis. The pharmxcological properties of cobra cardiotoxin have been extensively studied (LEE et al., 1968 ,1972; CHANG et al., 1972). This toxin affects various kinds of cells to produce skeletal muscle contracture, smooth muscle contraction, local irritation, direct hemolysis and cytotoxic action on HeLa, KB and Yoshida sarcoma cells. In this paper, a comparative study on the chemical and pharmacologicalproperties of the isolated cardio-toxin-like principles from Bungarus fasciatus and cobra venom are described.
    關聯: 嘉南學報, n.1 pp.118-130 轉載
    显示于类别:[嘉南學報] 1期 (1975)



    在CNU IR中所有的数据项都受到原著作权保护.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈