Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/28415
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    標題: N6-Substituted Adenosine Derivatives: Radioprotection, Whole Body Distribution, and Their Effects on Blood Preseure and Respiration Rates.
    作者: Asakura H
    Lee K
    Ikegami S
    Shikita M
    Akaboshi S
    貢獻者: 私立嘉南藥學專科學校
    放醫研藥學研究部
    東京大學醫學部放射醫學教室
    國立清華大學核科學研究所
    日期: 1976
    上傳時間: 2014-12-25 15:03:39 (UTC+8)
    摘要: Six derivatives of adenosine were examined on their pharmacological actions and whole body distribution in relation to their radioprotective action. They all caused a large drop in blood pressure and slowdown of pules rats. Respiration rate was slightly decreased with concomitant overbreathing. Labeled compounds of two of these adenosine derivatives, N-(14C-2-hydroxyethyl) adenosine and N(35S-2-mercaptoethyl) adenosine, were synthesized. Whole body autoradiographic study in mice showed a significant accumulation of the compounds in liver, spleen, intestinal mucosa and bone marrow.
    關聯: 嘉南學報, n.2 pp.A16-A21 轉載 Journal of radiation research, v.15 n.1 pp.19-24 (1974)
    显示于类别:[嘉南學報] 2期 (1976)

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