Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/27917
English  |  正體中文  |  简体中文  |  Items with full text/Total items : 18057/20255 (89%)
Visitors : 1508757      Online Users : 823
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/27917


    Title: Risk of Hospitalization for Acute Cardiovascular Events among Subjects with Lower Urinary Tract Symptoms: A Nationwide Population-Based Study
    Authors: Lin, Huey-Juan
    Weng, Shih-Feng
    Yang, Chun-Ming
    Wu, Ming-Ping
    Contributors: 化妝品應用與管理系
    通識教育中心
    醫務管理系
    Keywords: Benign Prostatic Hyperplasia
    Quality-Of-Life
    Overactive Bladder
    Erectile Dysfunction
    Nervous-System
    Health-Care
    Men
    Antimuscarinics
    Incontinence
    Prevalence
    Date: 2013-06
    Issue Date: 2014-05-26 10:48:56 (UTC+8)
    Publisher: Public Library Science
    Abstract: Background and Purpose: Lower urinary tract symptoms (LUTS) have been reported to be associated with metabolic syndrome and may predispose subjects to cardiovascular disease. The magnitude of the impact on the medical care remains to be elucidated. Based on a population-based claims dataset in Taiwan, we explored the association between LUTS and the risk of subsequent hospitalization for acute cardiovascular events.Materials and Methods: Among a representative sample of one million subjects from nationwide health insurance enrollees, subjects with codes of LUTS in service claims and without previous cardiovascular diseases including stroke were compared with age-and sex-matched non-LUTS subjects in subsequent hospitalization for acute coronary syndrome or stroke from the recruited date (between 2001-2004) to 2009. The risk of outcomes was assessed with Kaplan-Meier curves and the impact of LUTS was estimated with Poison regression analysis and Cox proportional hazards models.Results: We included 4,553 LUTS subjects and 22,765 matched non-LUTS subjects, with a mean age of 47 years and 43% of men. Hypertension, diabetes, and hyperlipidemia were more prevalent in the LUTS group. The incidence rate of the composite endpoint was significantly higher in the LUTS group than in the non-LUTS group (5.4/1000 vs. 4.0/1000 person-years). The difference mainly derived from stroke rather than acute coronary syndrome. After adjusting for age, sex, diabetes, hypertension, and hyperlipidemia in multivariable analysis, LUTS remained a significant predictor (hazard ratio, 1.29; 95% confidence incidence, 1.06-1.50).Conclusion: Subjects free of cardiovascular disease and presenting with LUTS are at risk of subsequent hospitalization for acute cardiovascular events, mainly stroke. The information might prompt practitioners encountering such patients to undergo appropriate diagnostic and preventive measures.
    Relation: Plos One, v.8 n.6, e66661
    Appears in Collections:[Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles
    [The Center For General Education] Periodical Articles
    [Dept. of Hospital and Health (including master's program)] Periodical Articles

    Files in This Item:

    File Description SizeFormat
    310902800_27917.pdf325KbAdobe PDF694View/Open
    index.html0KbHTML2009View/Open


    All items in CNU IR are protected by copyright, with all rights reserved.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback