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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/27826

    標題: Development of a protocol to solidify native and artificial oil bodies for long-term storage at room temperature
    作者: Chang, Ming-Tsung
    Chen, Chun-Ren
    Liu, Ting-Hang
    Lee, Chin-Pei
    Tzen, Jason T. C.
    貢獻者: 藥學系
    關鍵字: Artificial Oil Bodies
    日期: 2013-04
    上傳時間: 2014-05-26 10:45:14 (UTC+8)
    出版者: Wiley-Blackwell
    摘要: BACKGROUND: Oil bodies isolated from sesame seeds coalesced to form large oil drops when they were solidified in a drying process commonly used for food products. The aim of this study was to develop a protocol to solidify oil bodies for long-term storage at room temperature. RESULTS: On the basis of testing several excipients, the coalescence of oil bodies could be effectively prevented when they were combined with mannitol. Sizes of oil bodies appeared similar under a light microscope before and after powderisation in combination with 70% or more mannitol. Artificial oil bodies were successfully generated with sesame oil, phospholipid and recombinant sesame caleosin. Following the developed protocol, native and artificial oil bodies were stably solidified in tablets. Both native and artificial oil bodies dissolved from the tablets remained stable after an accelerated stress test under a condition of 75% humidity at 40 degrees C for 4 months. CONCLUSION: A protocol was successfully developed for the solidification of native and artificial oil bodies in stable powder and tablet forms. This successful protocol is very likely to expedite the utilisation of artificial oil bodies in their potential applications. (c) 2012 Society of Chemical Industry
    關聯: Journal of the Science of Food And Agriculture, v.93 n.6 pp.1516-1519
    Appears in Collections:[藥學系(所)] 期刊論文

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