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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/27808


    標題: Comparison of protective effects of three varieties of sugarcane leaves on oxidative stress in Clone 9 cells
    作者: Lee, Chia-Pu
    Chen, Zong-Tsi
    Yu, Pei-Ying
    Yen, Wen-Ye
    Lin, Kuo-Min
    Duh, Pin-Der
    貢獻者: 食品科技系
    醫藥化學系
    關鍵字: Clone 9 Cells
    Protective Effect
    Oxidative Stress
    Sugarcane Leaves
    日期: 2013-04
    上傳時間: 2014-05-26 10:44:31 (UTC+8)
    出版者: Elsevier Science Bv
    摘要: The protective effects of water extracts of sugarcane (Saccharum officinarum L.) leaves among three varieties, including 28NG256, wild type, and ROC10, on t-BHP-induced oxidative stress in Clone 9 cells were systematically compared. Among these three varieties, 28NG256 showed the highest protective effect against 0.2 mM t-BHP-induced oxidative stress in Clone 9 cells. In addition, 28NG256 displayed higher inhibitory effects on ROS generation than wild type and ROC10. Moreover, 28NG256 showed higher positive regulated GSH levels and antioxidant enzymes as well as higher protective potential against cell death by inhibiting caspase-3 activity and mitochondrial membrane depolarization. Chlorogenic and caffeic acids present in 28NG256 decreased significantly the generation of ROS, which may partly be responsible for the effect of Clone 9 cell growth. Thus, 28NG256, among the three varieties studied, showed the most protective effects against t-BHP-induced oxidative stress in Clone 9 cells. (C) 2013 Elsevier Ltd. All rights reserved.
    Appears in Collections:[ 食品科技系 ] 期刊論文
    [醫藥化學系 ] 期刊論文

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