Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/27765
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 17109/19415 (88%)
造访人次 : 2690789      在线人数 : 492
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.cnu.edu.tw/handle/310902800/27765


    標題: Abdominal Obesity Is Associated with Peripheral Artery Disease in Hemodialysis Patients
    作者: Hung, Peir-Haur
    Tsai, Hung-Bin
    Lin, Chien-Hung
    Hung, Kuan-Yu
    貢獻者: 生活應用與保健系
    關鍵字: C-Reactive Protein
    Stage Renal-Disease
    Coronary-Heart-Disease
    Chronic Kidney-Disease
    Blood-Pressure Index
    Treatment Panel-Iii
    Metabolic Syndrome
    Cardiovascular Mortality
    Inflammatory Markers
    Occlusive Disease
    日期: 2013-06
    上傳時間: 2014-05-26 10:42:45 (UTC+8)
    出版者: Public Library Science
    摘要: Background: Peripheral arterial disease (PAD) is a leading cause of morbidity in hemodialysis (HD) patients. Recent evidence suggests that abdominal obesity (AO) may play a role in PAD. However, the association between AO and PAD has not been thoroughly studied in HD patients.Methods: The present cross-sectional study aimed to examine the relationship between AO and PAD in a cohort of 204 chronic HD patients. The ankle brachial index (ABI) was used as an estimate of the presence of PAD. Plasma adiponectin levels, interleukin-6 (IL-6) levels, high sensitivity C-reactive protein (hs-CRP) levels, asymmetric dimethylarginine (ADMA) levels, and lipid profiles were measured. Logistic regression was used to estimate the association between the presence of PAD and AO as well as other potential risk factors.Results: The metabolic risk factors and all individual traits, including elevated ln-transformed hs-CRP, were found to be significant (P<0.05) more frequently in HD patients with AO than that in control subjects. Patients with AO had a higher prevalence of PAD than the control individuals, with a mean ABI of 0.96 +/- 0.23 and 1.08 +/- 0.16 (P<0.0001) and PAD prevalence of 26.9% and 10.8% (P=0.003), respectively. By multivariate analysis, AO (odds ratio [OR], 4.532; 95% CI, 1.765-11.639; P=0.002), elevated serum ln-transformed ADMA (OR, 5.535; 95% CI, 1.323-23.155; P=0.019), and ln-transformed IL-6 (OR, 1.567; 95% CI, 1.033-2.378; P=0.035) were independent predictors of the presence of PAD.Conclusions: HD patients with AO exhibited a cluster of metabolic risk factors and lower ABI. AO, elevated serum lntransformed ADMA, and ln-transformed IL-6 were independent predictors of the presence of PAD.
    显示于类别:[生活應用與保健系] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    index.html0KbHTML832检视/开启


    在CNU IR中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈