Antioxidant and Anti-Inflammatory Properties of Longan (Dimocarpus longan Lour.) Pericarp

doi:10.1155/2012/709483

CNU IR > Pharmacy and Science > Dept. of Cosmetic Science and institute of cosmetic science > Periodical Articles > Item 310902800/27704

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/27704

Title:	Antioxidant and Anti-Inflammatory Properties of Longan (Dimocarpus longan Lour.) Pericarp
Authors:	Huang, Guan-Jhong Wang, Bor-Sen Lin, Wei-Chao Huang, Shyh-Shyun Lee, Chao-Ying Yen, Ming-Tsung Huang, Ming-Hsing
Contributors:	化妝品應用與管理系
Keywords:	Oxidative Stress Free-Radicals Fruit Rat Inflammation Glutathione Mechanisms Chemistry Extract Enzymes
Date:	2012
Issue Date:	2014-03-21 16:18:13 (UTC+8)
Publisher:	Hindawi Publishing Corporation
Abstract:	This study examined the antioxidant and anti-inflammatory activities of the water extract of longan pericarp (WLP). The results showed that WLP exhibited radical scavenging, reducing activity and liposome protection activity. In addition, WLP also inhibited lipopolysaccharide (LPS)-induced nitric oxide (NO) production in macrophages. Further, administration of WLP, in the range of 100-400 mg/kg, showed a concentration-dependent inhibition on paw edema development following carrageenan (Carr) treatment in mice. The anti-inflammatory effects of WLP may be related to NO and tumor necrosis factor (TNF-alpha) suppression and associated with the increase in the activities of antioxidant enzymes, including catalase, superoxide dismutase, and glutathione peroxidase. Overall, the results showed that WLP might serve as a natural antioxidant and inflammatory inhibitor.
Relation:	Evidence-Based Complementary And Alternative Medicine, 709483,10 pages
Appears in Collections:	[Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles

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