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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/27704


    標題: Antioxidant and Anti-Inflammatory Properties of Longan (Dimocarpus longan Lour.) Pericarp
    作者: Huang, Guan-Jhong
    Wang, Bor-Sen
    Lin, Wei-Chao
    Huang, Shyh-Shyun
    Lee, Chao-Ying
    Yen, Ming-Tsung
    Huang, Ming-Hsing
    貢獻者: 化妝品應用與管理系
    關鍵字: Oxidative Stress
    Free-Radicals
    Fruit
    Rat
    Inflammation
    Glutathione
    Mechanisms
    Chemistry
    Extract
    Enzymes
    日期: 2012
    上傳時間: 2014-03-21 16:18:13 (UTC+8)
    出版者: Hindawi Publishing Corporation
    摘要: This study examined the antioxidant and anti-inflammatory activities of the water extract of longan pericarp (WLP). The results showed that WLP exhibited radical scavenging, reducing activity and liposome protection activity. In addition, WLP also inhibited lipopolysaccharide (LPS)-induced nitric oxide (NO) production in macrophages. Further, administration of WLP, in the range of 100-400 mg/kg, showed a concentration-dependent inhibition on paw edema development following carrageenan (Carr) treatment in mice. The anti-inflammatory effects of WLP may be related to NO and tumor necrosis factor (TNF-alpha) suppression and associated with the increase in the activities of antioxidant enzymes, including catalase, superoxide dismutase, and glutathione peroxidase. Overall, the results showed that WLP might serve as a natural antioxidant and inflammatory inhibitor.
    Appears in Collections:[化妝品應用與管理系(所)] 期刊論文

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