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    標題: Antioxidant and anti-inflammatory activities of aqueous extracts of Schizonepeta tenuifolia Briq.
    作者: Wang, Bor-Sen
    Huang, Guan-Jhong
    Tai, Huo-Mu
    Huang, Ming-Hsing
    貢獻者: 食品科技系
    化妝品應用與管理系
    關鍵字: Schizonepeta Tenuifolia
    Antioxidative
    Anti-Inflammatory
    Hplc
    日期: 2012-03
    上傳時間: 2014-03-21 16:17:13 (UTC+8)
    出版者: Pergamon-Elsevier Science Ltd
    摘要: This study investigated the antioxidative and anti-inflammatory activities of aqueous extracts of Schizonepeta tenuifolia Briq. (STE). The results showed that STE displayed radical scavenging and reducing activity, as well as liposome protection activity. In addition, the implementation of an HPLC with a photodiode array detector helped to identify polyphenolic components including hesperidin, luteolin, and diosmetin. STE administration in the range of 125-500 mg/kg showed concentration dependent inhibition on carrageenan induced inflammatory response in mice. The anti-inflammatory effects of STE could be related to tissue NO and tumor necrosis factor a (TNF-alpha) suppression, and associated with the reduction of lipid peroxidation and an increase in antioxidant enzyme activities including catalase, superoxide dismutase, and glutathione peroxidase in vivo. Overall, the results showed that STE might serve as a natural inhibitor of oxidation and inflammation. (C) 2011 Elsevier Ltd. All rights reserved.
    關聯: Food And Chemical Toxicology, 50(3-4), 526-531
    顯示於類別:[ 食品科技系 ] 期刊論文
    [化妝品應用與管理系(所)] 期刊論文

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