Melanogenesis Inhibition by Homoisoflavavone Sappanone A from Caesalpinia sappan

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Title:	Melanogenesis Inhibition by Homoisoflavavone Sappanone A from Caesalpinia sappan
Authors:	Chang, Te-Sheng Chao, Shih-Yu Ding, Hsiou-Yu
Contributors:	化妝品應用與管理系
Keywords:	Caesalpinia Sappan Inhibition Melanogenesis Sappanone A Tyrosinase
Date:	2012-08
Issue Date:	2014-03-21 16:14:33 (UTC+8)
Publisher:	Mdpi Ag
Abstract:	Homoisoflavanone, sappanone A, was isolated from Caesalpinia sappan and proven to dose-dependently inhibit both melanogenesis and cellular tyrosinase activity via repressing tyrosinase gene expression in mouse B16 melanoma cells. To our knowledge, sappanone A is the first homoisoflavanone to be discovered with melanogenesis inhibitory activity. Our results give a new impetus to the future search for other homoisoflavanone melanogenesis inhibitors.
Relation:	International Journal of Molecular Sciences, 13(8), 10359-10367
Appears in Collections:	[Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles

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