Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/27098
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    Title: Effects of Vitamin B-6 Deficiency on the Developing Central Nervous System of Rats Ⅱ. Analysis of Cerebellar Dimension
    維生素乙6缺乏對白鼠中樞神經系統的影響 第二報.小腦蚓部縱切面及其各層次面積,以及細胞密度之研究
    Authors: Chang, Sue-Joan
    Contributors: 私立嘉南藥學專科學校
    Date: 1981
    Issue Date: 2013-11-12 13:50:15 (UTC+8)
    Abstract: The influence of maternal vitamin B-6 deficiency on the cerebellar dimension of developing rats was studied at 15, 21 and 50 days of age. Cerebellar dimension was determined by measuring the linear drawing and counting the cells at the midsagittal vermis. Linear drawings of the cerebellum indicated that the areas of the cerebellum and the molecular, granular and medullary layers, as well as the length of the Purkinje cell layer, were decreased significantly in the deficient group (0.6mg pyridoxine HCl/kg diet) compared to those of the control (7.0 mg pyridoxine.HCl /kg diet) .Cell counts of the 0.6 group indicated an increased Purkinje cell density at 21 and 50 days and granule cell density at 50 days. In conclusion, a maternal vitamin B-6 deficiency revealed smaller areas of the cerebellum and its component layers in progeny, and was, therefore, associated with an increase in the cell density.
    Appears in Collections:[Chna Nan Annual Bulletin] Vol.7 (1981)

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