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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/26703


    標題: Inhibitory effects of molasses on mutation and nitric oxide production
    作者: Wang, Bor-Sen
    Chang, Lee-Wen
    Kang, Zhi-Chyang
    Chu, Heuy-Ling
    Tai, Huo-Mu
    Huang, Ming-Hsing
    貢獻者: 生活應用與保健系
    食品科技系
    保健營養系(所)
    化粧品應用與管理系
    關鍵字: Molasses
    Mutation
    Nitric oxide
    Lipopolysaccharide
    Antioxidation
    日期: 2011-06
    上傳時間: 2013-06-20 15:52:57 (UTC+8)
    出版者: Elsevier
    Amer Soc Microbiology
    摘要: In this study, the effects of four molasses related products including cane molasses (CM), carob molasses (CAM), grape molasses (GM), and sorghum molasses (SM) on the antimutation and nitric oxide (NO) production were examined. The results showed that the four molasses products, particularly CAM, inhibited the mutagenicity of 2-aminoanthracene (2-AA), an indirect mutagen; and 4-nitroquinoline-N-oxide (4-NQO), a direct mutagen in Salmonellatyphimurium TA98 and TA100. In addition, CAM also showed a higher ABTS radical inhibition, reducing activity, and decreasing lipid oxidative damage more than the others kinds of molasses. In the range of 0–0.8 mg/ml, the inhibitory effect of all molasses products on NO generation in lipopolysaccharide (LPS) stimulated macrophages increased with increasing concentrations, and CAM showed the best inhibition of NO production. These data suggested that the four molasses related products display their biological activities in terms of antioxidation, antimutation, and anti-inflammation.
    Appears in Collections:[生活應用與保健系] 期刊論文
    [ 食品科技系 ] 期刊論文
    [保健營養系(所) ] 期刊論文
    [化妝品應用與管理系(所)] 期刊論文

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