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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/26702


    標題: Effects of the aqueous extract of sugarcane leaves on antimutation and nitric oxide generation
    作者: Wang, Bor-Sen
    Duh, Pin-Der
    Wu, She-Ching
    Huang, Ming-Hsing
    貢獻者: 生活應用與保健系
    食品科技系
    化粧品應用與管理系
    關鍵字: Sugarcane leaves
    Mutation
    Nitric oxide
    Lipopolysaccharide
    Polyphenolics
    日期: 2011-01
    上傳時間: 2013-06-20 15:52:54 (UTC+8)
    出版者: Elsevier
    Elsevier Sci Ltd
    摘要: In this study, the effects of a water extract of sugarcane leaves (WSL) on antimutation and nitric oxide (NO) production were investigated. The results showed that WSL inhibited the mutagenicity of benzo[a]pyrene (BP), an indirect mutagen; and N-methyl-N′-nitrosoguanidine (MNNG), a direct mutagen toward Salmonella typhimurium TA 98 and TA 100. In addition, WSL, in the range of 0–0.4 mg/ml, showed superoxide inhibiting, NO scavenging, and reducing activity, as well as decreased lipid oxidative damage. In the range of 0–1 mg/ml, the inhibitory effect of WSL on NO generation in lipopolysaccharide (LPS) stimulated macrophages increased with increasing concentrations. A high performance liquid chromatography analysis revealed that the polyphenolic constituents, such as caffeic acid, ferulic acid, apigenin, and vitexin were present in WSL. These data suggested that WSL exhibiting biological activities could contribute to antimutation, anti-inflammation as well as antioxidation.
    Appears in Collections:[生活應用與保健系] 期刊論文
    [ 食品科技系 ] 期刊論文
    [化妝品應用與管理系(所)] 期刊論文

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