Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/23477
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    Title: Studies on Hypotensive Constituents of Limnophila Rugosa
    田香草之降血壓成分研究
    Authors: Mon-Chun Liu
    Zong-Shiow Chena
    Li-Ching Chung
    Meei-Shieu Yang
    Shien-Tsong Ho
    Ming-Tyan Chen
    Contributors: 應用化學科
    醫務管理科
    工業安全衛生科
    Keywords: Limnophila Rugosa
    3Beta-Hydroxylup-20(29)-en-27-oic acid
    Nevadensin
    Demethoxysudachitin
    Hypotensive activity
    Date: 1991
    Issue Date: 2011-01-04 16:44:54 (UTC+8)
    Abstract: The isolation and identification of 3 /3-hydorxylup-20(29)-en-27-oic acid, nevadensin, and demethoxysudachitin from the whole herb of Limnophila rugosa (Roth) Merr., Scrophulariaceae, were described. Nevadensin (3.1 mg/kg, i. v.) exhibited hypotensive effett on both normotensive and spontaneous hypertensive rate under pentobarbital anesthetization. After administration of nevadensin,The mean arterial pressure(MAP) of rates decreased about 50 mmHg for 30 min.
    本研究自田香草(Limnophila rugosa (Roth) Merr ., Scrophulariaceae)全草分離鑑定3B-hydroxylup-20(29)-en-27-oic acid, nevadensin 和 demethoxysudachitin 三種結晶性成分。Nevadensin(3.1mg/kg,i.v.)對於經pentobarbital麻醉的正常血壓與自發性高血壓大白鼠可降低平均動脈血壓50mmHg並持續30分鐘。
    Appears in Collections:[Chna Nan Annual Bulletin] Vol.17 (1991)
    [Dept. of Medicinal Chemistry] Periodical Articles
    [Dept. of Hospital and Health (including master's program)] Periodical Articles
    [Dept. of Occupational Safety] Periodical Articles

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