Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/23217
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 18034/20233 (89%)
造访人次 : 23353509      在线人数 : 474
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/23217


    標題: Effect of selected organo-sulfur compounds on melanin formation
    作者: Heuy-Ling Chu
    Bor-Sen Wang
    Pin-Der Duh
    貢獻者: 食品科技系
    關鍵字: Organo-sulfur compounds
    melanin
    tyrosinase
    reactive oxygen species
    日期: 2009-07
    上傳時間: 2010-11-15 11:27:11 (UTC+8)
    摘要: The effect of organo-sulfur compounds, including 1-propylmercaptan (PM), dimethyl disulfide (DMDS), diallyl disulfide (DADS), propyl disulfide (PDS), and 2,5-dimethylthiophene (DMT), on melanin formation was investigated. Among the selected five organo-sulfur compounds, PM displayed a significant inhibitory effect on tyrosinase activity (IC50 = 0.5 mM) and the highest inhibitory action on o-quinone formation. In the B16 intracellular model system, the inhibitory action of selected five organo-sulfur compounds on tyrosinase activity and melanin formation may be, in part, attributed to the reduction of the reactive oxygen species (ROS) formation and positive modulation of the GSH/GSSG ratio in B16 cells. Among the five organo-sulfur compounds, PM appeared to be the most potent inhibitor of melanin formation. The analysis of inhibitory kinetics revealed that PM is a mixed-type inhibitor. This is the first study indicating that organo-sulfur compounds tested may play an important role in the regulation of melanin formation, making them the potent candidates for skin-whitening agents.
    關聯: J.Agric Food Chem 57(15):p.7072-7077
    显示于类别:[ 食品科技系 ] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    index.html0KbHTML1847检视/开启


    在CNU IR中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈