A number of studies indicate that lactic acid bacteria (LAB) posses antioxidant properties and may prevent DAN damage induced by reactive oxygen species (ROS), like hydrogen peroxide. In this study, the antioxidant activities of LAB were monitored and investigated the prevention of oxidative DNA damage by isolated LAB cells. Some of these isolated strains reduced the DNA damage induced by H2O2. Addition experiments indicated that the reduction of oxidative damage is seen in fermented culture than in cell free extracts. When chemopreventive activity of LAB was evaluated, our data showed that LAB was able to reduce the DNA damage induced by H2O2 at pre and simultaneous protocols than post treatment.
International Conference for 2008『Nutraceuticals, Functional Foods and Dietary Supplements』，起迄日：2008/11/14~2008/11/17，地點：長榮桂冠酒店