Recent neuropschological research revealed dysfunction of the vestibular system in significant numbers of children were identified as sensory integration and learning disabled. The vestibular system, together with other visual system, proprioceptive system, and the cerebellum, serves for regulating posture, muscle tone, body equilibrium, spatial orientation, and eye-head coordination. The syndrome of vestibular bilateral integration is partially characterized as poor equilibrium reactions, poor oculomotor control, remnants of primitive postural reflexes, hypotonic muscle tone, and abnormal responses to vestibular stimulation. The other vestibular dysfunction is called gravitational incoordination caused by vestibular hyperactivity. However, a lot of factors can induce dysfunction of vestibular system. Data analysis revealed that mother health during pregnancy, including the safety of foods, smoking, drugs, and the baby care also affected the children’s vestibular development. The findings supported the hypothesis that behavior-impaired children have relatively greater neuropsychological involvement exhibited significantly low or high vestibular activity. In onclusion, the factors of mothers’ health during pregnancy, baby care mode and suitable environmental stimulation affected the sensory integration development, such as sensory motor development deficit children in Tainan.