2-溴芳香基烯晴的自由基環合反應位置選擇性之研究

CNU IR > Pharmacy and Science > Dept. of Cosmetic Science and institute of cosmetic science > MOST Project > Item 310902800/1850

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/1850

Title:	2-溴芳香基烯晴的自由基環合反應位置選擇性之研究 Studies on the Free-Radical Regioselective Cyclization of 2-Bromoaryl Alkenenitriles
Authors:	楊朝成 Chau-Chen Yang
Contributors:	化妝品應用與管理系
Keywords:	溴苯氧基烯晴環化反應甲基溴苯胺基烯晴溴苯硫基烯晴自由基 Bromophenoxy alkenenitrile Cyclization Methyl bromoanilino alkenenitrile Bromophenylthio alkenenitrile Free radical
Date:	1999
Issue Date:	2008-07-18 16:22:55 (UTC+8)
Publisher:	台南縣：嘉南藥理科技大學化妝品應用與管理系
Abstract:	本計畫主要研究2-溴芳香基烯晴化合物藉由三丁基錫烷在AIBN催化下,形成芳香基自由基,在氰基位置進行分子內加成反應之後,再與雙烯進行一次環合反應並進一部氧化得到一系列之雜環化合物。 This Thesis describes the regiochemistry Intramolecular cyclization of 2-(bromophenylthio)-2,4-alkadienenitriles 3, 5 and 2-(2-bromophenoxy)-2,4-alkadienenitriles 4, 6, which treatment with Bu3SnH reduced to generate an aryl free radical and underwent cyclization at the cyano group to give iminoradical. The iminoradical had the potential to undergo electrocyclization and subsequent oxidative aromation to afford heterocyclic compounds (Such as 5H-benzo[4,5]thiolo[3,2-b]azines, 5H-benzo[4,5]oxolo[3,2-b] azines).
Relation:	計畫編號：NSC88-2113-M-041-003
Appears in Collections:	[Dept. of Cosmetic Science and institute of cosmetic science] MOST Project

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