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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/1094


    標題: Investigation of solid products for lycopene(2)Formulation and Dissolution of hydrophobic drugs
    含茄紅素之固體製劑研發(2)脂溶性藥品之處方與溶離
    作者: 許立人
    貢獻者: 藥學系
    關鍵字: Soft capsule
    軟膠囊
    日期: 2003
    上傳時間: 2008-06-26 10:40:07 (UTC+8)
    出版者: 台南縣:嘉南藥理科技大學藥學系
    摘要: Soft capsules as a pharmaceutical dosage form have the advantages of being: high bioavailability for nonpolar drug in oil solution, stable toward oxidation and hydrolysis, and content uniformity. However, it has also some limitations such as: the raw material is animal origin, it breaks up in the stomach fast. The purpose of this study is to optimize the technology to make the soft capsule by a semi-automatic soft capsule machine. Then, add the function of controlled release to this traditional dosage form of soft capsule. Finally, do a preliminary screening study on the replacement or modification of the raw material.
    軟膠囊具有,對水難溶解性藥品高生體可用率之優點,同時內容均勻且安定,空氣及溼氣對膠囊之通透性皆低。
    但是它也有動物來源之缺點,對素食者不適用。而且狂牛病之傳染,使得人們更有疑慮。
    本計劃繼續研究半自動軟膠囊機製造軟膠囊之技術,也尋找開發軟膠囊之新原料。
    關聯: 計畫編號:CNPH9212
    Appears in Collections:[藥學系(所)] 校內計畫

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